128442-41-1Relevant academic research and scientific papers
Resolution of synthetically useful myo-inositol derivatives using the chiral auxiliary O-acetylmandelic acid
Sureshan, Kana M.,Kiyosawa, Yoko,Han, Fushe,Hyodo, Sayuri,Uno, Yuhki,Watanabe, Yutaka
, p. 231 - 241 (2007/10/03)
Efficient methods for the resolution of various myo-inositol derivatives have been developed using O-acetylmandelic acid (OAM) as the chiral auxiliary. Various methods of introduction of the chiral auxiliary have been compared. DCC mediated coupling betwe
Practical synthesis of all inositol stereoisomers from myo-inositol
Chung, Sung-Kee,Kwon, Yong-Uk
, p. 2135 - 2140 (2007/10/03)
Synthesis of six inositol stereoisomers was successfully carried out via conduritol intermediates prepared from myo-inositol. Dihydroxylation and epoxidation followed by ring opening of the conduritol B, C and F derivatives gave epi-, allo-, muco-, neo-, DL-chiro- and scyllo-inositol. The cis- inositol derivative, which may not be prepared by this approach, was synthesized in 5 steps via 2-O-benzoyl-myo-inositol orthoformate as the key intermediate.
A Chiral Synthesis of D-myo-Inositol 1-Phosphate Starting from L-Quebrachitol
Akiyama, Takahiko,Takechi, Naoto,Ozaki, Shoichiro,Shiota, Kenji
, p. 366 - 372 (2007/10/02)
A naturally occurring optically active cyclitol, L-quebrachitol (1L-2-O-methyl-chiro-inositol), was stereoselectively transformed into myo-inositol derivatives via an oxidation-reduction process.The methyl ether was cleaved chemoselectively with AlCl3NaI
Chiral synthesis of D-Myo-inositol 1-phosphate starting from L-querbrachitol
Akiyama,Takechi,Ozaki
, p. 1433 - 1434 (2007/10/02)
D-Myo-inositol 1-phosphate was synthesized from L-quebrachitol via stereoselective inversion of a 3-hydroxyl group and chemoselective demethylation.
SYNTHESIS OF SOME BENZYL AND METHYL ETHERS OF myo-INOSITOL
Garegg, Per J.,Lindberg, Bengt,Kvarnstroem, Ingemar,Svensson, Stefan C. T.
, p. 205 - 216 (2007/10/02)
The 1D and 1L forms of 1,2,4,5,6- and 1,2,3,4,5-penta-O-methyl-myo-inositol have been prepared from the corresponding chiral mono-O-benzyl derivatives.Convenient preparations are also described of achiral derivatives of 1-, 2-, 4-, and 5-O-benzyl-myo-inos
