131567-11-8

Basic information

• Product Name: (+/-)-7-chloro-8-hydroxy-3-methyl-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
• Synonyms: (+/-)-7-chloro-8-hydroxy-3-methyl-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
• CAS NO: 131567-11-8
• Molecular Weight: 366.685
• Mol File: 131567-11-8.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-7-chloro-8-hydroxy-3-methyl-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-7-chloro-8-hydroxy-3-methyl-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine(131567-11-8)
• EPA Substance Registry System: (+/-)-7-chloro-8-hydroxy-3-methyl-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine(131567-11-8)

Safety Data

• Hazardous Substances Data: 131567-11-8(Hazardous Substances Data)

Upstream product

• 55-81-2 4-Methoxyphenethylamine 
• 131567-07-2 (+/-)-7-chloro-8-methoxy-1-(3'-bromophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 28022-44-8 2-(3-bromophenyl)oxirane 
• 285978-33-8 1-(3-bromo-phenyl)-2-{[2-(3-chloro-4-methoxy-phenyl)-ethyl]-methyl-amino}-ethanol 
• 7569-58-6 2-(3-chloro-4-methoxyphenyl)acetonitrile 
• 7569-90-6 (3-chloro-4-methoxy-phenethyl)-methyl-amine 
• 7569-87-1 3-chloro-4-methoxyphenethylamine 
• 13719-57-8 3-chloro-4-methoxybenzyl chloride 
• 131567-09-4 (+/-)-7-chloro-8-methoxy-1-(3'-bromophenyl)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine 

Relevant articles and documents

Cyclopentadienyltricarbonylrheniumbenzazepines: Synthesis and binding affinity

Analogues of the benzazepine dopamine D1 receptor antagonist SCH-23390 incorporating the cyclo-pentadienyltricarbonyl-rhenium (CPTR) moiety were synthesized and evaluated pharmacologically. The CPTR derivatives retained affinity (0.3-2.9 nM) an

Synthesis and Resolution of (+/-)-7-Chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (TISCH): A High Affinity and Selective Iodinated Ligand for CNS D1 Dopamine Receptor

The synthesis and resolution of (+/-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, (+/-)-TISCH (8) has been achieved by resolution of intermediate 4, the O-methoxyl, 3'-bromo derivative, as the diastereomeric camphor