131674-40-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(2-methoxy-3-pyridinyl)(9CI) is utilized as an intermediate in the synthesis of various pharmaceuticals due to its versatile chemical properties. Its potential biological activities make it a valuable candidate for drug development, contributing to the creation of new medications.
Used in Agrochemical Industry:
Ethanone, 1-(2-methoxy-3-pyridinyl)(9CI) also serves as a key component in the production of agrochemicals, where it can be employed to develop novel pesticides or other agricultural products, enhancing crop protection and yield.
Used as a Flavoring Agent in the Food Industry:
Ethanone, 1-(2-methoxy-3-pyridinyl)(9CI) is used as a flavoring agent to impart specific tastes to food products, capitalizing on its unique chemical structure to create distinct flavor profiles.
Used as a Fragrance Ingredient in Cosmetics:
In the cosmetics industry, Ethanone, 1-(2-methoxy-3-pyridinyl)- (9CI) is employed as a fragrance ingredient, adding pleasant scents to various cosmetic products, leveraging its aromatic properties to enhance consumer appeal.
Overall, Ethanone, 1-(2-methoxy-3-pyridinyl)(9CI) has a wide range of industrial applications due to its unique chemical properties, making it a versatile compound in multiple sectors.

Upstream product

• 926003-56-7 N,2-dimethoxy-N-methylnicotinamide 
• 75-16-1 methylmagnesium bromide 
• 16498-81-0 2-methoxynicotinic acid 
• 131674-39-0 2-chloro-3-(1-hydroxyethyl)pyridine 
• 109-09-1 2-chloropyridine 
• 67-56-1 methanol 
• 169229-08-7 pyridocyclobuten-5-one 
• 55676-21-6 3-acetyl-2-chloropyridine 
• 124-41-4 sodium methylate 

Downstream Products

• 27038-46-6 3-(2-bromoacetyl)pyridin-2(1H)-one 

Relevant academic research and scientific papers

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy

Nrf2 activators represent a good drug target for designing agents to treat diseases associated with oxidative stress. Building upon previous work, we designed and prepared a series of heterocyclic chalcone-based Nrf2 activators with reduced lipophilicity

FUNCTIONALIZED HETROARYL ENONES EXHIBITING NRF2 ACTIVATION AND THEIR METHOD OF USE

Pharmaceutical compositions are disclosed, which include functionalized hetroaryl enones and are useful for treating or preventing a disease, disorder or condition associated with an NRF2-regulated pathway and/or which involves oxidative stress.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE

A 10a-azalide compound having a 4-membered ring structure crosslinked at the 10a- and 12-positions, which is represented by the formula (I), and is effective on even Haemophilus influenzae, or erythromycin resistant bacteria (e.g., resistant pneumococci and streptococci).

Synthesis of Pyridocyclobuten-5-one and 1-Azafulvenallene by Flash Vacuum Pyrolysis of 3-Chloroformyl-2-methylpyridine

The temperature and pressure dependence of products formed on pyrolysis of 3-chloroformyl-2-methylpyridine (6) have been studied.Pyrolysis of 6 at 575 deg C and ca. 1 x 10-4 torr gives pyridocyclobuten-5-one (5) in 20percent yield.Pyrolysis of 6 at 575 and 800 deg C and under the pressure of ca. 1 x 10-2 torr give 1-azafulvenallene (7, 46percent) and 1-cyanocyclopentadiene (8, 42percent), respectively.Irradiation of 5 (λ > 300 nm) in methanol affords 2-methoxy-3-acetylpyridine (9) quantitatively.

Improved Synthesis of 2,3-Disubstituted Pyridines by Metallation of 2-Chloropyridine: a Convenient Route to Fused Polyheterocycles

Chemoselective directed metallation of 2-chloropyridine allows the synthesis of 2-substituted 3-carbonylated pyridines, advantage being taken of the metallation ortho-directing effect of the halogen, as well as its reactivity towards nucleophiles.Thus (2-chloro-, 2-methoxy-, and 2-amino-3-pyridyl)-ethanones and -arylmethanones as well as carbaldehydes have been prepared.Some of these ortho-disubstituted intermediates have been readily cyclized to fused polyheterocycles such as naphthiridines and aza-analoges of coumarins, xanthones, and acridones.