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(6-Trifluoromethyl-pyridin-2-yl)-methanol is a chemical compound with the molecular formula C7H6F3NO. It is a pyridine derivative featuring a trifluoromethyl group and a hydroxyl group attached to the pyridine ring. (6-Trifluoromethyl-pyridin-2-yl)-methanol is recognized for its potential in the pharmaceutical and agrochemical industries, primarily serving as a building block for synthesizing biologically active molecules. The trifluoromethyl group is particularly valuable for enhancing the potency and metabolic stability of drug molecules, while the hydroxyl group provides versatility in the synthesis of medicinal and agricultural compounds.

131747-53-0

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131747-53-0 Usage

Uses

Used in Pharmaceutical Industry:
(6-Trifluoromethyl-pyridin-2-yl)-methanol is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its trifluoromethyl group is known to improve the potency and metabolic stability of drug molecules, making it an essential component in the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, (6-Trifluoromethyl-pyridin-2-yl)-methanol serves as a building block for the creation of biologically active compounds used in agriculture. Its properties contribute to the development of effective pesticides and other agrochemical products designed to protect crops and enhance agricultural productivity.
The hydroxyl group present in (6-Trifluoromethyl-pyridin-2-yl)-methanol allows for further chemical modifications and reactions, making it a versatile intermediate for the synthesis of a wide range of compounds with potential applications in both medicinal and agricultural chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 131747-53-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,4 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 131747-53:
(8*1)+(7*3)+(6*1)+(5*7)+(4*4)+(3*7)+(2*5)+(1*3)=120
120 % 10 = 0
So 131747-53-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3NO/c8-7(9,10)6-3-1-2-5(4-12)11-6/h1-3,12H,4H2

131747-53-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name [6-(trifluoromethyl)pyridin-2-yl]methanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131747-53-0 SDS

131747-53-0Relevant articles and documents

NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

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, (2020/11/12)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

NOVEL OXALYL PIPERAZINES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

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, (2020/11/12)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

ARYLAMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

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Page/Page column 291; 292, (2017/11/10)

The present invention relates to arylamide derivatives having dual pharmacological activity towards both the α2δ subunit, in particular the α2δ-1 subunit,of the voltage-gated calcium channel and the μ-opioid receptor, to processes of preparation of such c

Copper-mediated perfluoroalkylation of heteroaryl bromides with (phen)CuRF

Mormino, Michael G.,Fier, Patrick S.,Hartwig, John F.

, p. 1744 - 1747 (2014/04/17)

The attachment of perfluoroalkyl groups onto organic compounds has been a major synthetic goal over the past several decades. Previously, our group reported phenanthroline-ligated perfluoroalkyl copper reagents, (phen)CuR F, which react with aryl iodides and aryl boronates to form the corresponding benzotrifluorides. Herein the perfluoroalkylation of a series of heteroaryl bromides with (phen)CuCF3 and (phen)CuCF 2CF3 is reported. The mild reaction conditions allow the process to tolerate many common functional groups. Perfluoroethylation with (phen)CuCF2CF3 occurs in somewhat higher yields than trifluoromethylation with (phen)CuCF3, creating a method to generate fluoroalkyl heteroarenes that are less accessible from trifluoroacetic acid derivatives.

SEROTONIN RECEPTOR MODULATORS

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Page/Page column 89, (2010/07/10)

The biphenyic compounds of formula (I) are serotonin modulators useful in the treatment of serotonin-mediated diseases.

OXIME ETHER DERIVATIVE AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE

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Page/Page column 116, (2010/08/22)

The present invention provides a novel oxime ether derivative represented by the following formula (I), or salt thereof, that can be industrially produced advantageously, and can function as a fungicide for agricultural and horticultural use that has reliable effects and can be used safely, and a fungicide for agricultural and horticultural use that contains at least one of these compounds as an active ingredient thereof. In addition, the present invention provides a novel ketone derivative that is a production intermediate of the oxime ether derivative.

PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS

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Page/Page column 71, (2010/10/20)

The present invention is directed to a novel process for preparing certain cysteine protease inhibitors.

HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

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Page/Page column 81, (2008/06/13)

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

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