155377-05-2

Basic information

• Product Name: 6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester
• Synonyms: 6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester ;methyl 6-(trifluoromethyl)picolinate;Methyl 2-(trifluoromethyl)-6-pyridinecarboxylate;Methyl 6-(trifluoroMethyl)pyridine-2-carboxylate;Methyl 6-trifluoroMethyl-2-pyridinecarboxylate;Enasidenib Intermediate 3
• CAS NO: 155377-05-2
• Molecular Formula: C₈H₆F₃NO₂
• Molecular Weight: 205.14
• Mol File: 155377-05-2.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 232.6 °C at 760 mmHg
• Flash Point: 94.5 °C
• Appearance: /
• Density: 1.331 g/cm³
• Vapor Pressure: 0.0584mmHg at 25°C
• Refractive Index: 1.446
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.97±0.10(Predicted)
• CAS DataBase Reference: 6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester(155377-05-2)
• EPA Substance Registry System: 6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester(155377-05-2)

Safety Data

• Hazardous Substances Data: 155377-05-2(Hazardous Substances Data)

Usage

Uses

Methyl 6-(Trifluoromethyl)picolinate is used in the design of a series of substituted pyridines for the treatment of depression.

InChI:InChI=1/C8H6F3NO2/c1-14-7(13)5-3-2-4-6(12-5)8(9,10)11/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 39890-95-4 2-chloro-6-trifluoromethylpyridine 
• 887583-52-0 6-(trifluoromethyl)pyridine-2-carbonitrile 
• 849830-15-5 methyl 6-iodopyridine-2-carboxylate 
• 368-48-9 2-(trifluoromethyl)pyridine 
• 189278-27-1 2-bromo-6-(trifluoromethyl)pyridine 
• 26218-75-7 methyl 6-Bromopicolinate 
• 131747-42-7 6-(trifluoromethyl)pyridine-2-carboxylic acid 
• 186581-53-3 diazomethane 
• 124-38-9 carbon dioxide 

Downstream Products

• 476472-37-4 2-(4-fluoro-phenyl)-3-oxo-3-(6-trifluoromethyl-pyridin-2-yl)-propionitrile 
• 1192356-23-2 2-(6-trifluoromethyl-pyridin-2-yl)-propan-2-ol 
• 1446502-11-9 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol 
• 1446507-68-1 4-chloro-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoro-methyl)-pyridin-4-yl)-1,3,5-triazin-2-amine 
• 1338372-54-5 (4-fluorophenyl)(3-(6-(trifluoromethyl)pyridin-2-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone 
• 883037-22-7 6-(trifluoromethyl)pyridine-2-carbohydrazide 

Relevant articles and documents

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