131747-69-8

Basic information

• Product Name: 2-Fluoropyridine-4-carboxaldehyde
• Synonyms: 2-FLUORO-4-FORMYLPYRIDINE;2-FLUOROPYRIDINE-4-CARBOXALDEHYDE;2-Fluoroisonicotinaldehyde;4-Pyridinecarboxaldehyde,2-fluoro-(9CI);2-Fluoro-4-pyridinecarboxaldehyde;2-Fluoropyridine-4-c;2-fluoro-3-forMylpyridine-4-carboxylic acid;2-fluoropyridin-4-carbaldehyde
• CAS NO: 131747-69-8
• Molecular Formula: C₆H₄FNO
• Molecular Weight: 125.1
• EINECS: 214-589-6
• Product Categories: PYRIDINE;Boronic Acid;Pyridines
• Mol File: 131747-69-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 218.5 °C at 760 mmHg
• Flash Point: 86℃
• Appearance: /
• Density: 1.257 g/mL at 25 °C
• Vapor Pressure: 0.181mmHg at 25°C
• Refractive Index: n20/D1.512
• Storage Temp.: ?20°C
• PKA: -2.40±0.10(Predicted)
• CAS DataBase Reference: 2-Fluoropyridine-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoropyridine-4-carboxaldehyde(131747-69-8)
• EPA Substance Registry System: 2-Fluoropyridine-4-carboxaldehyde(131747-69-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36/38-22
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT, KEEP COLD
• Hazardous Substances Data: 131747-69-8(Hazardous Substances Data)

Usage

Uses

2-Fluoropyridine-4-carbaldehyde is used in the synthesis of quinolinyl analogs for α-synuclein aggregates.

InChI:InChI=1/C10H5BrF6O/c11-4-8(18)5-1-6(9(12,13)14)3-7(2-5)10(15,16)17/h1-3H,4H2

Upstream product

• 79-37-8 oxalyl dichloride 
• 131747-60-9 (2-fluoropyridin-4-yl)methanol 
• 402-65-3 2-fluoropyridine-4-carboxylic acid 
• 461-87-0 2-fluoro-4-methylpyridine 
• 695-34-1 2-Amino-4-methylpyridine 

Downstream Products

• 51-17-2 benzoimidazole 
• 1556954-17-6 (S)-methyl 3-cyclopropyl-3-(2-((4-(5-fluoro-2-methoxypyridin-4-yl)-3-((R)-1-methoxy-2,2-dimethylpropyl)benzyl)oxy)pyridin-4-yl)propanoate 
• 1426961-58-1 (3S,4S)-3-ethyl-4-(3-fluoropyridin-4-yl)-3-phenyloxetan-2-one 
• 1426961-67-2 (3S,4R)-3-ethyl-4-(3-fluoropyridin-4-yl)-3-phenyloxetan-2-one 
• 84940-51-2 4-(difluoromethyl)-2-fluoropyridine 
• 1349698-02-7 4-[(E)-2-(2-fluoropyridin-4-yl)vinyl]-N-methylaniline 
• 1349698-27-6 tert-butyl {4-[(E)-2-(2-fluoropyridin-4-yl)vinyl]phenyl}methylcarbamate 
• 1251531-66-4 (2E,6E)-2,6-bis((2-fluoropyridin-4-yl)methylene)cyclohexanone 
• 108338-11-0 2,6-Dimethyl-4-(2-fluoro-4-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-(N-benzyl-N-methylamino)ethyl ester 5-methyl ester 

Relevant articles and documents

8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXAMIDE DERIVATIVE

Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like.)

Substituted benzimidazoles

Compounds of formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in whose course an increased activity of NFκB is involved.