132274-03-4Relevant articles and documents
The first total synthesis of (-)-sinulariol-B and three other cembranoids
Lan, Jiong,Li, Jing,Liu, Zuosheng,Li, Yulin,Chan, Albert S. C.
, p. 1877 - 1885 (2007/10/03)
The first total synthesis of (-)-sinulariol-B, a marine cembrandiol, was achieved from geraniol. Three other cembranoids were also synthesized from (- )-sinulariol-B.
Novel Synthesis of (-)-(R)-Cembrene A, Synthesis of (+)-(R)-Cembrenene and (+)-(S)-Cembrene
Farkas, Imre,Pfander, Hanspeter
, p. 1980 - 1985 (2007/10/02)
A novel synthesis of (-)-(R)-cembrene A ((-)-3) was developed using the Sharpless epoxidation for the introduction of the chiral center.Furthermore, the synthesis of (+)-(R)-cembrenene ((+)-4) showed that this cembranoid must have the (R)-configuration and not, as previously reported, the (S)-confguration.Selective hydrogebation of (+)-4 afforded (+)-(S)-cembrene ((+)-5).
