132719-12-1

Basic information

• Product Name: 1-Octanone, 2-methyl-1-phenyl-
• CAS NO: 132719-12-1
• Molecular Formula: C15H22O
• Molecular Weight: 218.339
• Mol File: 132719-12-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-Octanone, 2-methyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Octanone, 2-methyl-1-phenyl-(132719-12-1)
• EPA Substance Registry System: 1-Octanone, 2-methyl-1-phenyl-(132719-12-1)

Safety Data

• Hazardous Substances Data: 132719-12-1(Hazardous Substances Data)

Upstream product

• 43152-88-1 (+)-2-methyl octanoic acid chloride 
• 71-43-2 benzene 
• 638-45-9 1-Iodohexane 
• 93-55-0 1-phenyl-propan-1-one 
• 67-56-1 methanol 
• 98-86-2 acetophenone 
• 111-27-3 hexan-1-ol 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 4128-31-8 rac-octan-2-ol 
• 98-85-1 1-Phenylethanol 
• 36049-78-2 2-iodooctane 
• 13939-06-5 molybdenum hexacarbonyl 
• 98-80-6 phenylboronic acid 
• 201230-82-2 carbon monoxide 

Downstream Products

• 609815-76-1 thiophosphoric acid S-(1-benzoyl-1-methylheptyl) ester O,O-diethyl ester 
• 609815-95-4 Trimethyl-((E)-2-methyl-1-phenyl-oct-1-enyloxy)-silane 

Relevant articles and documents

Oxidizing Action of Hydroperoxides. Oxidation of Alkyl Aryl Ketones by Hydroperoxides

The oxidation of alkyl aryl ketones by t-butyl hydroperoxide under basic conditions gave products which resulted from the fission of the carbon-carbon bond between carbonyl carbon and alkyl carbon.The reaction was investigated using chiral alkyl aryl ketones.On the basis of the results, a probable reaction mechanism is proposed.

Heterogeneously catalyzed direct cross-coupling of secondary alcohols to β-disubstituted ketones by Cu/γ-Al2O3

This study describes the development of Cu/γ-Al2O3 heterogeneously catalyzed cross-coupling of secondary alcohols reaction in the construction of β-disubstituted ketones. Noteworthy, the study reports for the first time, the application of a heterogeneous catalyst in the direct cross-coupling of secondary alcohols. Mechanistic investigations indicate that the activation of alcohols via the cooperation of Cu and γ-Al2O3 plays a crucial role in cross-coupling reactions. This reaction exhibited good substrate compatibility, and the catalyst exhibited constant efficiency even after five reaction cycles. This novel methodology can be applied as a powerful, low-cost, and safe technology for the construction of β-disubstituted ketones.

Palladium and visible-light mediated carbonylative Suzuki-Miyaura coupling of unactivated alkyl halides and aryl boronic acids

Herein, a simple and efficient method for the palladium-catalyzed carbonylation of aryl boronic acids with unactivated alkyl iodides and bromides under visible-light irradiation, ambient temperature and low CO-pressure is presented. Notably, the procedure uses readily available equipment and an inexpensive palladium catalyst to generate the key alkyl radical intermediate. These mild conditions enabled the synthesis of a range of functionalized aryl alkyl ketones including the antipsychotic drug, melperone.

Iridium-catalyzed selective α-methylation of ketones with methanol

Iridium-catalyzed selective α-dimethylation and α-methylation of ketones or phenylacetonitriles, using methanol as the methylating agent, were achieved. In addition, three-component cross α-methyl-alkylation was successfully performed using methyl ketones with methanol and primary alcohols with long-chain alkyl groups. This method provides a very convenient direct route to α-methylated ketones, using methanol.