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1329063-72-0

C46H48N6O6 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1329063-72-0 Structure

  • Basic information

    1. Product Name: C46H48N6O6
    2. Synonyms: C46H48N6O6
    3. CAS NO:1329063-72-0
    4. Molecular Formula:
    5. Molecular Weight: 780.924
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1329063-72-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C46H48N6O6(CAS DataBase Reference)
    10. NIST Chemistry Reference: C46H48N6O6(1329063-72-0)
    11. EPA Substance Registry System: C46H48N6O6(1329063-72-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1329063-72-0(Hazardous Substances Data)

1329063-72-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1329063-72-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,2,9,0,6 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1329063-72:
(9*1)+(8*3)+(7*2)+(6*9)+(5*0)+(4*6)+(3*3)+(2*7)+(1*2)=150
150 % 10 = 0
So 1329063-72-0 is a valid CAS Registry Number.

1329063-72-0Relevant articles and documents

Targeting the prostaglandin f2α receptor for preventing preterm labor with azapeptide tocolytics

Bourguet, Carine B.,Goupil, Eugénie,Tassy, Dana?,Hou, Xin,Thouin, Eryk,Polyak, Felix,Hébert, Terence E.,Claing, Audrey,Laporte, Stéphane A.,Chemtob, Sylvain,Lubell, William D.

, p. 6085 - 6097 (2011/11/05)

The prostaglandin-F2α (PGF2α) receptor (FP) was targeted to develop tocolytic agents for inhibiting preterm labor. Azabicycloalkane and azapeptide mimics 2-10 were synthesized based on the (3S,6S,9S)-indolizidin-2- one amino acid analogue PDC113.824 (1), which was shown to modulate FP by a biased allosteric mechanism, involving both Gαq- and Gα12-mediated signaling pathways, and exhibited significant tocolytic activity delaying preterm labor in a mouse model (Goupil; et al.J. Biol. Chem. 2010, 285, 25624-25636). Although changes in azabicycloalkane stereochemistry and ring size caused loss of activity, replacement of the indolizidin-2-one amino acid with azaGly-Pro and azaPhe-Pro gave azapeptides 6 and 8, which reduced PGF2α-induced myometrial contractions, potentiated the effect of PGF2α on Gαq-mediated ERK1/2 activation, and inhibited FP modulation of cell ruffling, a response dependent on the Gα12/RhoA/ROCK signaling pathway. Revealing complementarities of azabicycloalkane and azapeptide mimics, novel probes, and efficient tocolytic agents were made to study allosteric modulation of the FP receptor.

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