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Usage

Uses

Used in Pharmaceutical Industry:
5-METHYL-2-PHENYL-3-PYRAZOLIDINONE is used as a pharmaceutical intermediate for the synthesis of various pharmaceutical products, particularly nonsteroidal anti-inflammatory drugs (NSAIDs). It plays a crucial role in the production of phenylbutazone, a drug used for its anti-inflammatory and analgesic properties.
Used in Organic Synthesis:
5-METHYL-2-PHENYL-3-PYRAZOLIDINONE is used as a reagent in organic synthesis, contributing to the development of new chemical compounds and materials.
Used in Dyes and Pigments Manufacturing:
5-METHYL-2-PHENYL-3-PYRAZOLIDINONE is used as a starting material in the manufacturing of dyes and pigments, enabling the creation of a wide range of colorants for various applications.

InChI:InChI=1/C10H12N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6,8,11H,7H2,1H3

Upstream product

• 3724-65-0 2-butenoic acid 
• 100-63-0 phenylhydrazine 
• 503-64-0 (Z)-but-2-enoic acid 
• 623-43-8 crotonic acid methyl ester 
• 89-25-8 edaravone 

Downstream Products

• 36755-40-5 2,2,7-trimethyl-5-phenyl-1-oxa-5,6-diazaspiro<2.4>hept-6-en-4-one 
• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 74451-57-3 (E)-5,5'-dimethyl-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione 
• 89-25-8 edaravone 
• 1392402-92-4 C₂₇H₂₂ClFN₄O₃S 
• 1392402-83-3 C₂₇H₂₃ClN₄O₃S 
• 1392402-84-4 C₂₇H₂₂Cl₂N₄O₃S 
• 1392402-85-5 C₂₇H₂₂Cl₂N₄O₃S 
• 1392402-86-6 C₂₇H₂₂ClN₅O₅S 
• 1392402-87-7 C₂₈H₂₅ClN₄O₄S 
• 1392402-88-8 C₂₇H₂₃ClN₄O₄S 
• 1392402-89-9 C₂₇H₂₃ClN₄O₄S 
• 1392402-90-2 C₂₉H₂₅ClN₄O₃S 
• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis of pyrazolones and pyrazoles via Pd-catalyzed aerobic oxidative dehydrogenation

A palladium-catalyzed oxidative dehydrogenation reaction in the presence of AMS and base to synthesize pyrazolones and pyrazoles was identified. This method can be utilized to a wide range of substrates, operates under mild react conditions and can give high yields. We believe it could be used as an alternative protocol for the classical dehydrogenation reactions.

Facile and highly regiospecific synthesis of 2-aryl-substituted pyrazolidin-3-ones from α,β-unsaturated N-acylbenzotriazoles and arylhydrazines

The bis-addition of arylhydrazines to α,β-unsaturated N-acylbenzotriazoles to form heterocyclic compounds was achieved in refluxing THF by using triethylamine as promoter. The reaction was highly regioselective and various 2-aryl-substituted pyrazolidin-3

Bipyrazole derivative, and medicine or reagent comprising the same as active component

A medicine or reagent comprising a bipyrazole derivative of the following formula (I), wherein R1 and R2 are individually a hydrogen atom, aryl group, alkyl group having 1-5 carbon atoms, or alkoxycarbonylalkyl group having a total of 3-6 carbon atoms, R3 and R4 are individually a hydrogen atom, alkyl group having 1-5 carbon atoms, cycloalkyl group having 5-7 carbon atoms, hydroxyalkyl group having 1-3 carbon atoms, benzyl group, naphthyl group, or substituted or unsubstituted phenyl group, as an active component. The medicine is useful for effectively capturing active oxygen and free radicals which cause adult diseases such as cerebral ischemia, heart disease, digestive system disease, and carcinoma, as well as inflammation, and for diagnosing diseases associated with in vivo free radicals.