133040-03-6

Basic information

• Product Name: METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE
• Synonyms: METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE;4-[(2-Butyl-5-forMyliMidazol-1-yl)Methyl]benzoic Acid Methyl Ester
• CAS NO: 133040-03-6
• Molecular Formula: C₁₇H₂₀N₂O₃
• Molecular Weight: 300.3523
• Product Categories: Aromatics Compounds;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 133040-03-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 72-74 °C
• Boiling Point: 473.8 °C at 760 mmHg
• Flash Point: 240.4 °C
• Appearance: /
• Density: 1.13 g/cm³
• Solubility: Dichloromethane, Methanol
• PKA: 4.26±0.34(Predicted)
• CAS DataBase Reference: METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE(133040-03-6)
• EPA Substance Registry System: METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE(133040-03-6)

Safety Data

• Hazardous Substances Data: 133040-03-6(Hazardous Substances Data)

Usage

Chemical Properties

Oil

Uses

Methyl 4-[(2-Butyl-5-formyl-1H-imidazol-1-yl)methyl]benzoate (cas# 133040-03-6) is a compound useful in organic synthesis.

InChI:InChI=1S/C17H20N2O3/c1-3-4-5-16-18-10-15(12-20)19(16)11-13-6-8-14(9-7-13)17(21)22-2/h6-10,12H,3-5,11H2,1-2H3

Upstream product

• 133040-02-5 2-butyl-4-chloro-1-<(4-carbomethoxyphenyl)methyl>-1H-imidazole-5-carboxaldehyde 
• 7440-44-0 pyrographite 
• 154371-51-4 1-(benzyloxymethyl)-2-butyl-4-iodoimidazole-5-carboxaldehyde 
• 154371-62-7 1-(benzyloxymethyl)-2-butyl-4,5-diiodoimidazole 
• 146771-83-7 2-butyl-4-iodoimidazole-5-carboxaldehyde 
• 154371-61-6 2-butyl-4,5-diiodoimidazole 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 68282-49-5 2-butyl-1H-imidazole-5-carboxaldehyde 
• 68283-19-2 2-butyl-5-hydroxymethyl-1H-imidazole 
• 83857-96-9 2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde 
• 18469-52-8 methyl 4-(aminomethyl)benzoate 
• 57246-71-6 methyl pentanimidate 
• 110-59-8 pentanonitrile 
• 50790-93-7 2-butyl-1H-imidazole 

Downstream Products

• 133040-04-7 2-butyl-1-(4-carbomethoxybenzyl)-5-<2-carbomethoxy-1-hydroxy-3-(2-thienyl)propyl>imidazole 
• 1236942-80-5 (E)-3-[2-n-Butyl-1-{(3-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-benzyl-2-propenoic Acid 
• 152146-59-3 2-n-butyl-1-[(4-carboxyphenyl)-methyl]-1H-imidazole-5-carboxaldehyde 
• 152146-88-8 methyl (E)-4-<<2-butyl-5-<(1-butyl-2,5-dioxo-4-imidazolidinylidene)methyl>-1H-imidazol-1-yl>methyl>benzoate 
• 152147-12-1 methyl Z-4-[[2-butyl-5-[(1-hexyl-2,5-dioxo-4-imidazolidinylidene)methyl]-1H-imidazol-1-yl]methyl]benzoate 
• 152147-22-3 methyl Z-4-[[2-butyl-5-[[1-(methoxymethyl)-2,5-dioxo-4-imidazolidinylidene]methyl]-1H-imidazol-1-yl]methyl]benzoate 
• 1104528-98-4 (E)-α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophene propanoic acid acetate 
• 133040-01-4 eprosartan 
• 1265625-28-2 2-butyl-1-(4-carbomethoxybenzyl)-5-[2-carboethoxy-3-(benzo[b]thiophen-2-yl)prop-1-enyl]-1H-imidazole 
• 159708-84-6 2-butyl-1-(4-methoxycarbonylbenzyl)-1H-imidazole-4-carboxylic acid 
• 159708-90-4 C₁₇H₂₀N₂O₄ 
• 133486-13-2 ethyl (αE)-α-[[2-n-butyl-1-[[4-(methoxycarbonyl)phenyl]methyl]-1H-imidazol-5-yl]methylene-2-thiophene]propionate 

Relevant articles and documents

DUAL-ACTING ANTIHYPERTENSIVE AGENTS

In one aspect, the invention relates to compounds having the formula: wherein: Ar, r, Z, X, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

IMPROVED PROCESS FOR EPROSARTAN

The present invention provides an improved and commercially viable process for preparation of eprosartan and its pharmaceutically acceptable acid addition salts thereof in high purity and in high yield. Thus, for example, methyl 4-[[2-butyl-5-formyl-1 H-i

Substituted imidazolyl-alkylthio-alkanoic acids

Angiotensin II receptor antagonists having the formula: STR1 which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.