133149-65-2

Basic information

• Product Name: 7-(4-Methoxy-phenyl)-9,11-dioxo-8,11-dihydro-9H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile
• CAS NO: 133149-65-2
• Molecular Weight: 368.351
• Mol File: 133149-65-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-(4-Methoxy-phenyl)-9,11-dioxo-8,11-dihydro-9H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-Methoxy-phenyl)-9,11-dioxo-8,11-dihydro-9H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile(133149-65-2)
• EPA Substance Registry System: 7-(4-Methoxy-phenyl)-9,11-dioxo-8,11-dihydro-9H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile(133149-65-2)

Safety Data

• Hazardous Substances Data: 133149-65-2(Hazardous Substances Data)

Upstream product

• 30750-23-3 2-(4-oxo-3,4-dihydroquinazolin-2-yl)acetonitrile 
• 2286-29-5 ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate 
• 133149-48-1 (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile 
• 133149-53-8 (Z)-2-Cyano-3-(4-methoxy-phenyl)-thioacrylimidic acid methyl ester 
• 118-92-3 anthranilic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 39145-31-8 2-cyano-3-(4-methoxyphenyl)thioacrylamide 

Relevant articles and documents

α-Cyanothioacetamide and its Derivatives in Heterocyclic Synthesis: Preparation of Several New 4-Oxoquinazoline Derivatives

The reaction of α-cyanothioacetamide (1) or its methylthio derivative (2) with anthranilic acid led to the formation of 3,4-dihydro-4-oxoquinazolin-2-yl acetonitrile (3). 3 condensed with aromatic aldehydes to give arylidene derivatives (4a-d) which could be prepared also via the reaction of 2-thiocarbamoylcinnamonitriles (5a-d) or their methylthio derivatives (6a-d) with anthranilic acid. 3 reacted with cinnamonitrile derivatives (7a-h) and (12a-d) to yield pyrido--quinazoline derivatives (10a-h) and (15a-d) which could also be prepared by the reaction of (4a-d) with malononitrile (11a), benzoyl acetonitrile (11b) and ethylcyanoacetate (16), respectively.