133156-35-1

Upstream product

• 33617-49-1 diethyl <3,5-bis(benzyloxy)benzyl>phosphonate 
• 100-52-7 benzaldehyde 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 67093-27-0 3,5-dibenzyloxybenzyl chloride 
• 100-39-0 benzyl bromide 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 21956-56-9 (E)-3,5-dimethoxystilbene 
• 22139-77-1 pinosylvin 
• 808771-18-8 pinosylvin monobenzyl ether 

Downstream Products

• 133156-38-4 1,3-Bis(methoxymethoxy)-2-geranyl-5-phenethylbenzol 
• 133156-37-3 1,3-Bis(methoxymethoxy)-2-(3-methyl-2-butenyl)-5-phenethylbenzol 
• 14531-52-3 dihydropinosylvin 
• 22139-77-1 pinosylvin 

Relevant academic research and scientific papers

Synthesis and inhibitory effects of pinosylvin derivatives on prostaglandin E2 production in lipopolysaccharide-induced mouse macrophage cells

The inhibitory effects of pinosylvin analogues on the production of COX-2 mediated PGE2 were evaluated in a cell culture system. A new series of potential inhibitors, including 3-hydroxy-5-benzyloxy-trans-stilbene and 3,5-dimethoxy-trans-stilbene, have been identified. A series of natural stilbenoids, pinosylvin and its derivatives, were synthesized and evaluated for the inhibitory activity of prostaglandin E2 production in lipopolysaccharide-induced RAW 264.7 cells. Potential inhibitors, including 3,5-dimethoxy-trans-stilbene and 3-hydroxy-5-benzyloxy-trans-stilbene, have been newly identified, and thus providing chemical leads for the further development of anti-inflammatory or cancer chemopreventive agents.

Synthesis of bryophyte components 2. Syntheses of prenylated bibenzyl derivatives

Efficient and expeditious syntheses of the biologically active prenylated bibenzyl derivatives 1a-d are developed giving rise to their access on a preparative scale.