133814-25-2

Basic information

• Product Name: DL-2-DIMETHYLAMINO-1-PROPANOL
• CAS NO: 133814-25-2
• Molecular Formula: C5H13NO
• Molecular Weight: 0
• Mol File: 133814-25-2.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DL-2-DIMETHYLAMINO-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: DL-2-DIMETHYLAMINO-1-PROPANOL(133814-25-2)
• EPA Substance Registry System: DL-2-DIMETHYLAMINO-1-PROPANOL(133814-25-2)

Safety Data

• Hazardous Substances Data: 133814-25-2(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 6168-72-5 2-Amino-1-propanol 
• 124-40-3 dimethyl amine 
• 598-72-1 2-Bromopropionic acid 
• 108-14-5 2-chloro-1-dimethylaminopropane 
• 152918-63-3 2-dimethylamino-3-methoxy-propionic acid 24-[8-acetoxy-6-(2-dimethylamino-propionyloxy)-2-hydroxy-11,11-dimethoxy-1,3,7,9-tetramethyl-undecyl]-10-hydroxy-14,20-dimethoxy-9,11,15,18-tetramethyl-2-oxo-oxacyclotetracosa-3,5,15,21-tetraen-8-yl ester 
• 157431-09-9 Ν,Ν-dimethyl D-alanine 
• 2749-11-3 (S)-Alaninol 
• 14352-99-9 (S)-(-)-N,N-Dimethylalaninethylester 
• 2812-31-9 N,N-dimethyl-L-alanine 
• 81408-31-3 (R)-1-[(4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4′-bi(1,3-dioxolan)-5-yl]ethanol 
• 42293-86-7 methyl (2S)-2-(dimethylamino)propanoate 
• 90726-76-4 Butyl-D(+)-2-dimethylaminopropionat 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 94914-83-7 benzilic acid-(2-dimethylamino-propyl ester) 
• 94439-61-9 Cyclohexyl-phenyl-glykolsaeure-<2-dimethylamino-propylester> 
• 15284-15-8 (+)-Methadone hydrochloride 
• 7576-08-1 (S)-(+)-2,2-diphenyl-4-dimethylaminopentanenitrile 
• 109478-13-9 3-(ethyl-dimethyl-ammonio)-propionic acid-[2-(ethyl-dimethyl-ammonio)-propylester]; diiodide 
• 93309-65-0 2-(2-Dimethylamino-propyloxy)-1-phenyl-ethanol-(1) 
• 4188-22-1 (β-hydroxy-isopropyl)-trimethyl-ammonium; iodide 
• 26290-68-6 1-Acetoxy-2-dimethylaminopropan-methiodid 

Relevant articles and documents

The absolute configurations of the alfa- and beta-methylcholine isomers and their acetyl and succinyl esters.

-

Chiral β-dimethylaminoalkylphosphines. Highly efficient ligands for a nickel complex catalyzed asymmetric grignard cross-coupling reaction

Chiral β-dimethylaminoalkylphosphines were prepared starting with amino acids, (S)-alanine, (S)-phenylalanine, (R)-phenylglycine, (S)-valine, and (R)-tert-leucine. The chiral phosphines were found to be highly efficient ligands for a nickel catalyzed asymmetric Grignard cross-coupling reaction (38～94% optical yield).

SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF

Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

4-ANILINO-QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS

A quinazoline derivative of the formula (I): wherein the substituents are as defined in the text for use in the production of an anti proliferative effect which effect is produced alone or in part by inhibiting erbB2 receptor tyrosine kinase in a warm blooded animal such as man.