13395-60-3

Basic information

• Product Name: 3-chloro-4'-methylbenzophenone
• Synonyms: Benzophenone,3-chloro-4'-methyl- (8CI); 3-Chloro-4'-methylbenzophenone
• CAS NO: 13395-60-3
• Molecular Formula: C₁₄H₁₁ClO
• Molecular Weight: 230.7
• Mol File: 13395-60-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 368.5°Cat760mmHg
• Flash Point: 198.8°C
• Appearance: /
• Density: 1.178g/cm³
• CAS DataBase Reference: 3-chloro-4'-methylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-4'-methylbenzophenone(13395-60-3)
• EPA Substance Registry System: 3-chloro-4'-methylbenzophenone(13395-60-3)

Safety Data

• Hazardous Substances Data: 13395-60-3(Hazardous Substances Data)

Usage

General Description

3-Chloro-4'-methylbenzophenone, also known as 4-methyl-3-chlorobenzophenone, is a chemical compound with the molecular formula C14H11ClO. It is a white solid with a melting point of 47-48°C and a boiling point of 332°C. 3-chloro-4'-methylbenzophenone is used as a UV absorber in the production of plastics and polymers, as well as in the synthesis of pharmaceuticals and agrochemicals. It is also utilized as an intermediate in the manufacturing of dyes, perfumes, and other organic compounds. However, it is important to handle this chemical with caution as it is considered harmful if swallowed, inhaled, or in contact with skin, and it may cause irritation to the eyes and respiratory system.

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 108-88-3 toluene 
• 874-60-2 4-methyl-benzoyl chloride 
• 108-90-7 chlorobenzene 
• 106-38-7 para-bromotoluene 
• 587-04-2 m-Chlorobenzaldehyde 
• 63503-60-6 3-chlorophenylboronic acid 
• 5720-05-8 4-methylphenylboronic acid 
• 535-80-8 3-chlorobenzoate 
• 624742-95-6 3-(4'-methylbenzoyl)phenyl radical 

Downstream Products

• 949934-34-3 C₂₃H₂₈Cl₂N₂O₂*ClH 
• 1014987-03-1 tert-butyl 4-(4-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)benzyl)piperazine-1-carboxylate 
• 949934-31-0 (3-chlorophenyl){4-[(N-tert-butoxycarbonylpiperazin-4-yl)methyl]phenyl}methanone 
• 949934-32-1 (3-chlorophenyl){4-[(N-tert-butoxycarbonylpiperazin-4-yl)methyl]phenyl}methanol 
• 927690-10-6 (+/-)-(3-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]phenylmethanol 
• 898776-32-4 (3-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone 
• 945657-22-7 (4-bromomethyl-phenyl)(3-chloro-phenyl)methanone 

Relevant articles and documents

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Supported Palladium-Catalyzed Carbonylative Synthesis of Diaryl Ketones from Aryl Bromides and Arylboronic Acids

A palladium supported on graphitic carbon nitride (Pd/g-C3N4) catalyzed carbonylative reaction of aryl bromides and arylboronic acids by has been developed for the construction of diaryl ketones. Using benzene-1,3,5-triyl triformate (TFBen) as the CO source, the reaction proceeded well to give various diaryl ketones in moderate to good yields.

NOVEL 4-AMINO-QUINOLINE DERIVATIVES USEFUL AS ANTI-MALARIA DRUGS

The present invention relates to clotrimazole/quinoline hybrids useful as active ingredients of anti-malaria drugs. The compounds show a remarkable in vitro biological activity especially against the chloroquine-resistant Plasmodium falciparum strains and