133988-97-3

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 93292-63-8 (S)-2-(tert-butyldiphenylsilyloxy)heptanal 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 93292-62-7 (2R,3S)-3-(tert-Butyl-diphenyl-silanyloxy)-octane-1,2-diol 
• 93292-61-6 tert-Butyl-[(S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hexyloxy]-diphenyl-silane 

Downstream Products

• 93292-64-9 (4S),(2E)-4-O-tert-butyldiphenylsilyloxy-2-nonenol 
• 93292-65-0 1-bromo-(4S),(2E)-4-tert-butyldiphenylsilyloxy-2-nonene 
• 93292-66-1 <(4S)-(2E)-4-tert-butyldiphenylsilyloxy-2-nonen-yl>triphenylphosphonium bromide 
• 94235-56-0 (5S,6R,15S)-(7E,9E,11Z,13E)-15-O-tert-butyldiphenylsilyl-5,6-O-carbonyllipoxin A₄ ethyl ester 
• 94292-89-4 4-{(4S,5R)-5-[(1E,3E,5E,7E)-(S)-9-(tert-Butyl-diphenyl-silanyloxy)-tetradeca-1,3,5,7-tetraenyl]-2-oxo-[1,3]dioxolan-4-yl}-butyric acid ethyl ester 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF LIPOXINS A4 AND B4 FROM D-ISOASCORBIC ACID

A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure α-hydroxy and α,β-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material.Connection by a six carbons unit uses Wittig-type reaction

Lipoxins A4 and B4. Total Synthesis Including Deprotection Studies

The total synthesis of lipoxins A4 and B4 (LXA4 and LXB4) as well as of their all-trans isomers is reported.A study concerning the final steps of deprotection of silyl ether, cyclic carbonate and ethyl ester assisted by a high-speed scanning UV spectropho