94292-89-4Relevant academic research and scientific papers
Synthesis of (2E,4E)-dienals by double formyl-olefination with an arsonium salt and its application in the syntheses of lipoxygenase metabolites of arachidonic acid
Peng, Zhi-Hui,Li, Yun-Long,Wu, Wen-Lian,Liu, Cui-Xian,Wu, Yu-Lin
, p. 1057 - 1066 (2007/10/03)
A new facile route to (2E,4E)-dienals by a double formyl-olefination with arsonium salts has been developed. By this method and with other arsonium reagents in the key step some lipoxygenase metabolites of arachidonic acid, lipoxin A4 and B4 and leukotriene B4, have been synthesized.
Lipoxins A4 and B4. Total Synthesis Including Deprotection Studies
Gravier-Pelletier, Christine,Dumas, Jacques,Merrer, Yves Le,Depezay, Jean-Claude
, p. 2441 - 2452 (2007/10/02)
The total synthesis of lipoxins A4 and B4 (LXA4 and LXB4) as well as of their all-trans isomers is reported.A study concerning the final steps of deprotection of silyl ether, cyclic carbonate and ethyl ester assisted by a high-speed scanning UV spectropho
TOTAL SYNTHESIS OF LIPOXINS A4 AND B4 FROM D-ISOASCORBIC ACID
Gravier-Pelletier, C.,Dumas, J.,Merrer, Y. Le,Depezay, J. C.
, p. 1165 - 1168 (2007/10/02)
A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure α-hydroxy and α,β-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material.Connection by a six carbons unit uses Wittig-type reaction
