1345509-87-6

Basic information

• Product Name: ethyl 2-phenyl-5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate
• Synonyms: ethyl 2-phenyl-5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate
• CAS NO: 1345509-87-6
• Molecular Weight: 318.375
• Mol File: 1345509-87-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-phenyl-5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-phenyl-5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate(1345509-87-6)
• EPA Substance Registry System: ethyl 2-phenyl-5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate(1345509-87-6)

Safety Data

• Hazardous Substances Data: 1345509-87-6(Hazardous Substances Data)

Upstream product

• 24423-87-8 3,4-dihydro-isoquinoline 2-oxide 
• 61013-61-4 ethyl 2-azido-3-phenylacrylate 
• 88014-09-9 (3,4-dihydro-1H-isoquinolin-2-yl)-acetic acid ethyl ester 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Cobalt-catalyzed oxidative [3 + 2] cycloaddition reactions: An efficient synthesis of pyrrolo- and imidazo-[2,1-a]isoquinolines

A cobalt-catalyzed oxidative [3 + 2] cycloaddition cascades of dihydroisoquinoline esters with nitroolefins or N-sulfuryl aldimines were developed at room temperature. A multi-component reaction for the synthesis of 5,6-dihydroimidazo[2,1-a]isoquinolines were also realized under almost identical conditions. This method is particularly suitable for the synthesis of tricyclic nitrogen heterocycles due to its simple manipulation, wide scope of the reaction substrates and excellent regioselectivity.