13456-39-8

Usage

InChI:InChI=1/C13H18N2O4/c1-3-14(4-2)9-10-19-13(16)11-5-7-12(8-6-11)15(17)18/h5-8H,3-4,9-10H2,1-2H3

Upstream product

• 99-99-0 1-methyl-4-nitrobenzene 
• 10342-59-3 1-nitro-4-propyl-benzene 
• 20651-75-6 1-butyl-4-nitro-benzene 
• 122-04-3 4-nitro-benzoyl chloride 
• 100-37-8 2-(Diethylamino)ethanol 
• 62-23-7 4-nitro-benzoic acid 
• 109-89-7 diethylamine 

Downstream Products

• 35943-98-7 (E)-3,7-dimethylocta-2,6-dien-1-yl 4-nitrobenzoate 
• 90224-92-3 4-nitro-benzoic acid-(2,2,2-tribromo-ethyl ester) 
• 97104-23-9 4-Nitro-benzoesaeure-(2-hydroxy-benzylester) 
• 26090-29-9 4-(2-Octyloxy-benzoylamino)-benzoic acid 2-diethylamino-ethyl ester 
• 26095-59-0 otilonium bromide 
• 150-13-0 4-amino-benzoic acid 
• 59-46-1 Procaine 
• 62-23-7 4-nitro-benzoic acid 
• 99-77-4 ethyl 4-nitrobenzoate 
• 94-09-7 p-aminoethylbenzoate 
• 16488-52-1 4-methylamino-benzoic acid-(2-diethylamino-ethyl ester) 

Relevant academic research and scientific papers

ANTIBIOTIC AMMONIUM COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present disclosure provides ammonium compounds, e.g., compounds according to Formula I as set forth herein, which are useful as antimicrobial agents. Methods for the treatment of bacterial infections and associated conditions, e.g., gastrointestinal conditions, are also described, as well as methods for altering the microbiome of subjects such as humans.

Metal-Free Aerobic Oxidation of Nitro-Substituted Alkylarenes to Carboxylic Acids or Benzyl Alcohols Promoted by NaOH

Efficient and selective aerobic oxidation of nitro-substituted alkylarenes to functional compounds is a fundamental process that remains a challenge. Here, we report a metal-free, efficient, and practical approach for the direct and selective aerobic oxidation of nitro-substituted alkylarenes to carboxylic acids or benzyl alcohols. This sustainable system uses O2 as clean oxidant in a cheap and green NaOH/EtOH mixture. The position and type of substituent critically affect the products. In addition, this sustainable protocol enabled gram-scale preparation of carboxylic acid and benzyl alcohol derivatives with high chemoselectivities. Finally, the reactions can be conducted in a pressure reactor, which can conserve oxygen and prevent solvent loss. The approach was conducive to environmental protection and potential industrial application.

Immobilised Candida antarctica B as efficient catalyst for the synthesis of local anaesthetic intermediates

We hereby present the development of new reaction conditions for the CALB catalysed esterification of substituted benzoic acids. Using cyclohexane as the reaction media a number of heptyl benzoates have been easily isolated in good to excellent yields (up to 100% at 80 C, 20-24 h). Moreover, the catalytic system has been successfully applied to the synthesis of local anaesthetics intermediates also showing good productivity in recycling experiments.