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Usage

Uses

Used in Organic Synthesis:
Benzaldehyde N-phenylthiosemicarbazone serves as a key intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities and pharmaceuticals.
Used in Analytical Chemistry:
As a reagent in analytical chemistry, benzaldehyde N-phenylthiosemicarbazone aids in the identification and quantification of specific substances, enhancing the accuracy and efficiency of analytical processes.
Used in Corrosion Inhibition:
benzaldehyde N-phenylthiosemicarbazone exhibits inhibitory properties against the corrosion of mild steel, making it a valuable asset in industries where metal protection is crucial, such as in the automotive and construction sectors.
Used in Antimicrobial Applications:
Due to its antifungal and antibacterial activities, benzaldehyde N-phenylthiosemicarbazone can be utilized in the development of antimicrobial agents for medical and industrial purposes, such as in the production of disinfectants and preservatives.
Used in Pharmaceutical Research:
Benzaldehyde N-phenylthiosemicarbazone is studied for its potential therapeutic applications in treating various diseases and disorders, including cancer and diabetes, offering new avenues for drug discovery and development.
Used in Industrial Settings:
Its versatility extends to industrial applications where it can be employed in the production of various products, from coatings and paints to textiles and plastics, due to its corrosion inhibition and antimicrobial properties.

Upstream product

• 100-52-7 benzaldehyde 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 64-17-5 ethanol 
• 5281-18-5 benzaldehyde, hydrazone 
• 103-72-0 phenyl isothiocyanate 
• 28867-76-7 benzaldehyde benzylidenehydrazone 
• 101569-98-6 Cinnamoylameisensaeure-<4-phenyl-thiosemicarbazon> 
• 7664-41-7 ammonia 
• 302-01-2 hydrazine 
• 34025-58-6 2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9-one 
• 108-94-1 cyclohexanone 
• 79-19-6 thiosemicarbazide 
• 51034-34-5 potassium aniline dithiocarbamate 
• 62-53-3 aniline 

Downstream Products

• 1437-57-6 5-Phenyl-2-phenylamino-1,3,4-thiadiazol 
• 53705-00-3 bis-{4,5-diphenyl-1,2,4-triazolyl-⁽³⁾}-disulfide 
• 67618-51-3 2-benzylidenehydrazono-3-phenyl-2,3-dihydro-thiazole-5-carboxylic acid ethyl ester 
• 98177-16-3 benzaldehyde (5-methyl-4-oxo-3-phenyl-thiazolidin-2-ylidene)-hydrazone 
• 2880-19-5 2-benzylidenehydrazono-4-methyl-3-phenyl-2,3-dihydro-thiazole-5-carboxylic acid ethyl ester 
• 139355-59-2 4-Phenyl-5-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-[1,2,4]dithiazolidin-3-one 
• 125791-41-5 (Z)-1-Phenyl-3-(2-phenyl-5-phenylamino-[1,3,4]thiadiazol-3-yl)-propenone 
• 1437-57-6 phenyl-(5-phenyl-3H-[1,3,4]thiadiazole-2-ylidene)amine 
• 1093399-52-0 4-amino-1-benzoyl-2,7-dinitro-4'-phenylspiro(fluoren-9,3'-[1,2,4]triazolidine)-5'-thione 
• 1437-57-6 phenyl-(5-phenyl-3H-[1,3,4]thiadiazol-2-ylidene)amine 
• 84409-01-8 4-amino-2,7-dinitro-9-fluorenone 
• 1093399-46-2 (1-benzoyl-4-phenyl-3-thioxo-1,2,4-triazaspiro[4.5]deca-6,9-dien-8-ylidene)malononitrile 
• 1093399-40-6 4a-hydroxy-3-phenylindeno[2,1-e][1,3,4]oxadiazin-9(4aH)-one 
• 1093399-45-1 3-cyano-4-oxo-N-phenylideno[1,2-c]pyrazole-1(4H)-carbothioamide 

Relevant academic research and scientific papers

A new "switch-On" fluorescence chemosensor for anions via modulation of intraligand and metal-to-ligand charge-transfer emission in a Pd(II)-based receptor

A new mechanism for anion sensing by fluorescence spectroscopy based on modulation of intraligand fluorescence (IL) and metal-to-ligand charge-transfer (MLCT) emission from a weakly fluorescent metal complex was investigated. Elemental analysis of the rec

PhI-Catalyzed Intramolecular Oxidative Coupling Toward Synthesis of 2-Amino-1,3,4-Thiadizoles

A highly efficient method for the synthesis of thiadiazole derivatives via intramolecular oxidative coupling of thiosemicarbazide, using the in situ generated hypervalent iodine(III) reagents is developed. The protocol can be carried out smoothly and provides a variety of thiadiazole derivatives in moderate to excellent yields. Graphical Abstract: A highly efficient method for the synthesis of thiadiazole derivatives via PhI-catalyzed intramolecular oxidative coupling of thiosemicarbazide has been developed.

Phenyl -2 - shrinkage N4 -Phenyl thiosemicarbazone aryl ruthenium complex as well as preparation method and application thereof

The invention discloses a phenyl-2-acetal N-phenyl thiosemicarbazide ruthenium aryl complex as well as a preparation method and application thereof. The complex has a structural formula (III) in the specification. The chemical name of the complex is trichloromonomethyl isopropylbenzene ruthenium (II) monochloro-phenyl-2-acetal N-phenyl thiosemicarbazide-methyl isopropylbenzene ruthenium (II). The complex shows good inhibitory activities towards gastric cancer SGC7901 cell lines and liver cancer BEL-7404 cell lines, can be used for preparing medicines for treating cancers, and can be used after being prepared into the forms, such as injections, tablets, pills, capsules, suspending agents or emulsion. The preparation method of the phenyl-2-acetal N-phenyl thiosemicarbazide ruthenium aryl complex is simple, is accessible in raw materials and has the advantage of low cost.

Cyclization of 4-phenylthiosemicarbazide with phenacylbromide revisited. Formation of 1,3,4-thiadiazines and of isomeric 1,3-thiazoles

The cyclization of 4-phenylthiosemicarbazide with phenacylbromide, carried out in refluxing ethanol, afforded 1,3,4-thiadiazine 1 as the major product. In contrast to a previous report, 2-phenylimino-4-phenyl-2,3-dihydro-1,3-thiazol-3- amine (2) and not 2

Synthesis and biological evaluation of novel benzoquinones as potential antimicrobial agents

New series of 2,5-dihydroxyphenyl-1,3-thiazoles 4a-l was synthesized by reacting 2,5-dihydroxyphenacyl bromide with various 4-aryl thiosemicarbazones 3a-l that on oxidation with ferric chloride yielded the corresponding N 1-substituted benzylid

Synthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1] nonan-9-one 4′-phenylthiosemicarbazones

New series of 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4′-phenylthiosemicarbazones (compounds 9-16) was obtained from the corresponding 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. The synthesized compounds have been characterized by their elemental, anal

Efficient synthesis of 1,3,4-thiadiazoles using hydrogen bond donor (thio)urea derivatives as organocatalysts

(Chemical Equation Presented) A simple and efficient procedure for the synthesis of 1,3,4-thiadiazoles has been achieved using thiourea as organocatalyst. In this study, the steric and electronic effects using structurally different derivatives of urea and thiourea in different solvents were evaluated. The best yields and the rate of the reactions were obtained using 30 mol % of thiourea as catalyst in acetonitrile at room temperature. The molecular structures of the products were established by 1H and 13C NMR spectral data.

One-pot and catalyst-free synthesis of thiosemicarbazones via multicomponent coupling reactions

A novel and efficient procedure for the synthesis of thiosemicarbazones has been achieved via a multicomponent and catalyst-free reaction of phenyl or p-chlorophenyl isothiocyanate, hydrazine, and aldehydes or ketones. The method afforded 20 thiosemicarba

Synthesis, characterization and thermal studies of some new organotin (IV) complexes with aniline N-thiohydrazide and benzaldehyde aniline N-thiohydrazone

The complexes of parachlorotribenzyltin (IV) chloride and parachlorodibenzyl tin (IV) dichloride with aniline N-thiohydrazide (L 1), and benzaldehyde aniline N-thiohydrazone (L2) have been synthesized. The complexes have been characterized by elemental analysis and spectral (UV-VIS, IR & NMR) studies. Ligand in the complexes acts as bidentate and coordination takes place through sulphur and terminal nitrogen. These are 1:1 metal ligand complexes. Various thermodynamic parameters have been calculated for the decomposition steps using TG-DTA curves. Activity of all the complexes Vs. Rhizoctonia bataticola fungal strain have been studied and the general order of activity have been deduced.

Synthesis and antibacterial activity of pyridyl thioureas and arylthiosemicarbazones

[N-(2-pyridyl)-N'-(4-(un) substituted] thioureas and (substitutedaryl)thiosemicarbazones were synthesised and evaluated for their antibacterial activity. All aryl thiosemicarbazones showed good activity against Aeromonas hydrophilia and Salmonella typhimuriurn. But none of the pyridyl thioureas showed any prominent activity against tested bacteria.