134575-13-6 Usage
Description
(1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol, also known as 3-Azabicyclo[3.1.0]hexane-6-methanol, is a bicyclic chemical compound with the molecular formula C7H13NO. It features a six-membered ring containing a nitrogen atom and is characterized by its unique structure and stereochemistry. (1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol is commonly utilized in organic synthesis and serves as a building block in the preparation of pharmaceuticals and agrochemicals, making it a versatile intermediate for the production of various chemical products. Its structural similarity to biologically active compounds also suggests potential applications in medicinal chemistry and drug discovery.
Uses
Used in Organic Synthesis:
(1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol is used as a key intermediate in organic synthesis for the production of a variety of chemical products. Its unique structure and stereochemistry allow for the creation of complex molecules with specific properties.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, (1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol is used as a building block for the development of new drugs. Its structural similarity to biologically active compounds makes it a valuable component in the synthesis of potential therapeutic agents.
Used in Agrochemical Development:
(1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol is also utilized in the agrochemical sector as a precursor for the synthesis of various agrochemicals, contributing to the development of effective crop protection products.
Used in Medicinal Chemistry and Drug Discovery:
Due to its structural resemblance to biologically active compounds, (1R,5S,6R)-3-Azabicyclo[3.1.0]hexan-6-ylmethanol is employed in medicinal chemistry and drug discovery research. It serves as a promising candidate for the design and development of novel therapeutic agents with potential applications in various medical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 134575-13-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,5,7 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 134575-13:
(8*1)+(7*3)+(6*4)+(5*5)+(4*7)+(3*5)+(2*1)+(1*3)=126
126 % 10 = 6
So 134575-13-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO/c8-3-6-4-1-7-2-5(4)6/h4-8H,1-3H2/t4-,5+,6+
134575-13-6Relevant articles and documents
A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF
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, (2022/03/07)
The present invention relates to a class of bifunctional chimeric heterocyclic compounds for targeted degradation of androgen receptors and use thereof, and specifically provides a compound of formula (I), or an isotopic compound thereof, or an optical isomer thereof, or a tautomer thereof, or a pharmacologically acceptable salt thereof, or a prodrug thereof, or a solvate thereof, wherein ARB is an androgen receptor recognition/binding part, L is a link part, and U is a ubiquitin protease recognition/binding part; and the three parts are connected by means of chemical bonds. The compound can perform the targeted degradation on androgen receptors in prostate cancer cells, and suppress the proliferation of the prostate cancer cells, and also show good metabolic stability and pharmacokinetic properties. The compound has good application prospect in the preparation of targeted chimeras for protein degradation of androgen receptors and in the preparation of drugs for treating the related diseases regulated by the androgen receptors.
Azabicyclo quinolone carboxylic acids
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, (2008/06/13)
Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity., Antibacterial wherein, R1 is hydrogen, a pharmaceutically acceptable cation, or alkyl;, Y, when taken independently, is ethyl, t-butyl, vinyl, cyclopropyl, 2-fluoroethyl, p-fluorophenyl, or o,p-difluorophenyl;, W is hydrogen, F, Cl, Br, alkyl, alkoxy, NH2, NHCH3;, A is CH, CF, CCl, COCH3, C-CH3, C-CN or N; or, A is carbon and is taken together with Y and the carbon and nitrogen to which A and Y are attached to form a five or six membered ring which may contain oxygen or a double bond, and which may have attached thereto R8 which is methyl or methylene; and, R2 is wherein R3, R4, R5, R6, R7, R9, R10 and R25 are each independently H, CH3, CH2NH2, CH2NHCH3 or CH2NHC2H5, and R5, R6, R7, and R9 may also independently be NH2, NHCH3 or NHC2H5.
