13475-17-7

Usage

Uses

Used in Pharmaceutical Industry:
4-ACETAMIDOPHENYLACETIC ACID ETHYL ESTER is used as a pharmaceutical intermediate for its role in the synthesis of various medicinal compounds and pharmaceutical products. It contributes to the development of drugs that target a range of health conditions due to its inherent biological and pharmacological properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4-ACETAMIDOPHENYLACETIC ACID ETHYL ESTER is used as a building block for the creation of new drug candidates. Its structural features make it a valuable component in the design and synthesis of innovative pharmaceuticals with potential therapeutic applications.
Used in Anti-inflammatory and Analgesic Applications:
4-ACETAMIDOPHENYLACETIC ACID ETHYL ESTER is studied for its potential use as an anti-inflammatory and analgesic agent. Its properties are harnessed in the development of medications aimed at reducing inflammation and alleviating pain, providing relief to patients suffering from various conditions.

InChI:InChI=1/C12H15NO3/c1-3-16-12(15)8-10-4-6-11(7-5-10)13-9(2)14/h4-7H,3,8H2,1-2H3,(H,13,14)

Upstream product

• 5438-70-0 ethyl (4-amino-3,5-dibromophenyl)acetate 
• 108-24-7 acetic anhydride 
• 5445-26-1 ETHYL 4-NITROPHENYLACETATE 
• 18699-02-0 4-acetamidophenylacetic acid 
• 64-17-5 ethanol 

Downstream Products

• 56203-27-1 2-(4-Acetylamino-phenyl)-N-[2-(2-hydroxy-2-phenyl-ethylamino)-ethyl]-acetamide 
• 36691-06-2 ethyl 2-(4-(1,3-dioxoisoindolin-2-yl)phenyl)acetate 
• 104126-70-7 2-(4-amino-3-nitrophenyl)acetic acid ethyl ester 
• 92959-74-5 ethyl 2-(4-acetamido-3-nitrophenyl)acetate 
• 1374606-51-5 ethyl 2-(4-acetamido-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate 
• 1374607-01-8 C₁₃H₁₄F₃NO₃ 
• 5438-70-0 ethyl (4-amino-3,5-dibromophenyl)acetate 

Relevant academic research and scientific papers

Rapid and Selective Cleavage of Amide Groups at Neutral pH: Applications from Hyaluronic Acid to Small Molecules

During our investigation to find suitable conditions to prepare very high molecular weight partially de-acetylated hyaluronic acid (HA), we discovered a powerful new method to cleave amide bonds using hydroxylamine salts at neutral pH with remarkable sele

DERIVATIVES OF ACTARIT AND THEIR THERAPEUTIC USE

Compounds that may have anti-inflammatory activity are of general formula wherein X is O or NR1; Y isOorNR1; R2 is OR1 or C,1-4 alkyl substituted with R3, and R2 is optionally substituted With R4; each R1 is the same or different and is H or C1-4 alkyl, or R1 and R2 are joined to form a four to seven-membered ring containing one or more additional heteroatoms selected from O, N and S, and is optionally substituted with R7; R3is OR4, NR5R6 or a four to seven- embered ring which can contain .one or morte heteroatoms selected from O, N and S, and is optionally substituted with R7;R4 is H or C1-4 alkyl optionally substituted with OR8; R5 and R6 are the same or different and are each selected from H and C1-4 alkyl optionally substituted with OR8; R7 is C1-4 alkyl optionally substituted with OR8, halogen, CF3, NR5R6, or S(O)nR9where n is 0-2; each R8 is H or C1-4 alkyl optionally substituted with halogen or OH; and R9 is C1-4 alkyl; and the salts, solvates and hydrates thereof.

An antibody transesterase derived from reactive immunization that utilizes a wide variety of alcohol substrates

A monoclonal antibody obtained from reactive immunization catalyzes transesterifications of alcohol substrates with both broad and unusual specificity.

Immunomodulating agent

Phenylacetic acid derivatives of the formula: STR1 wherein R1 is hydrogen or STR2 wherein R5 is an alkyl group of 1-6 carbon atoms or an aryl group; R2 and R3 are independently hydrogen or an alkyl group of 1-4 carbon atoms; R4 is hydrogen or an alkyl group of 1-4 carbon atoms, have been found to possess immunomodulating activity.