134891-99-9

Basic information

• Product Name: Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester
• CAS NO: 134891-99-9
• Molecular Formula: C11H19O4P
• Molecular Weight: 246.243
• Mol File: 134891-99-9.mol

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester(134891-99-9)
• EPA Substance Registry System: Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester(134891-99-9)

Safety Data

• Hazardous Substances Data: 134891-99-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester is used as a key intermediate in the synthesis of pharmaceuticals for its potential antioxidant and anti-inflammatory properties, contributing to the development of new drugs with therapeutic benefits.
Used in Agrochemical Industry:
Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester is also utilized in the synthesis of agrochemicals, where its properties may contribute to the development of effective and environmentally friendly products for agricultural applications.
Used in Metal Chelation Therapy:
Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester has been studied for its potential use in metal chelation therapy, where it could be employed for the treatment of heavy metal poisoning by safely binding and removing toxic metals from the body.
Further research is necessary to fully understand the properties and potential applications of Phosphonic acid, [(3-oxo-1-cyclohexen-1-yl)methyl]-, diethyl ester, ensuring its safe and effective use across various industries.

Upstream product

• 16807-60-6 3-methoxycyclohex-2-en-1-one 
• 683-08-9 Diethyl methylphosphonate 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 818-38-2 Diethyl glutarate 
• 23740-61-6 2-(phenylsulfanyl)-2-cyclohexanone 
• 67502-51-6 diethyl [(phenylselanyl)methyl]phosphonate 
• 930-68-7 cyclohexenone 
• 84978-80-3 2-(phenylsulfinyl)cyclohex-2-en-1-one 
• 173171-39-6 diethyl <(1-hydroxy-3-chloro-2-cyclohexen-1-yl)methyl>phosphonate 
• 153983-68-7 [7-(Diethoxy-phosphoryl)-2,6-dioxo-heptyl]-phosphonic acid diethyl ester 
• 134891-93-3 <(1-hydroxy-2-cyclohexen-1-yl)methyl>phosphonate 
• 5682-75-7 3-chloro-2-cyclohexenone 

Downstream Products

• 29179-03-1 (E)-3-(prop-1-en-1-yl)cyclohex-2-en-1-one 
• 209402-40-4 diethyl (3-oximinocyclohex-1-enyl)methylphosphonate 
• 1096156-00-1 3-(4-(diphenylamino)styryl)cyclohex-2-enone 
• 60815-18-1 diethyl [(3-methoxyphenyl)methyl]phosphonate 

Relevant articles and documents

A General Approach to 3-Phosphorylmethyl Cycloalkenones by Intramolecular Horner-Wittig Reaction of Bis-β-ketophosphonates

The reaction of dicarboxylic acid diesters with lithiomethylphosphonates was found to give bis-β-keto phosphonates 1 2(CH2)n (n = 2, 3, 4), a new class of compounds.Their cyclization under basic conditions provides an easy access to five

Structurally simple dipolar organic dyes featuring 1,3-cyclohexadiene conjugated unit for dye-sensitized solar cells

(Chemical Equation Presented) A series of structurally simple dipolar light-harvesting organic dyes featuring 1,3-cyclohexadiene in the aromatic π framework for dye-sensitized solar cells has been synthesized and characterized. The highest conversion effi

Synthesis of 3-(phosphorylmethyl)cycloalkenones by forced conjugate addition of α-phosphonate carbanions to cyclic enones

Cycloalkenones were found to react with α-lithiated diethyl (phenylselanyl)methylphosphonate preferentially or exclusively at the carbonyl group giving 1,2-adducts. When complexes of cycloalkenones with aluminum tris(2,6-diphenylphenoxide) were used for t

Reaction of Phosphonate-Stabilized Carbanions with Cyclic Enones Bearing a β-Leaving Group

Reaction between α-lithiated alkylphosphonic esters and α,β-unsaturated cyclopentenones and cyclohexenones carrying a heteroatom substituent Y in the β-position was studied.Complete chemoselectivity was observed as a function of substituent Y.For Y = OMe exclusive addition-elimination at the β-carbon was observed, yielding α,β-unsaturated δ-ketophosphonates.The β-chloro-substituted substrates (Y = Cl) derived from cyclohexenone reacted exclusively at the carbonyl carbon, yielding (2-hydroxyalkyl)phosphonates with the retained chlorovinyl function.The alcohols, depending on the conditions, could be dehydrated to two different products.The reaction of 3-chlorocyclopent-2-en-1-one with diethyl (lithiomethyl)phosphonate occured at the β-carbon, but the ketophosphonate product was isolated in a stable enolic form.

Oxidative rearrangement of phosphorus containing tertiary allylic alcohols: Synthesis of (3-oxo-1-cycloalkenyl)phosphonates, -methylphosphonates, -methyldiphenylphosphine oxides and their epoxy derivatives

Regioselective 1,2-addition of dimethylphosphite, diethyl (lithiomethyl)phosphonate, or (lithiomethyl)diphenylphosphine oxide to 2-cyclopenten-1-one (1a) or 2-cyclohexen-1-one (1b) affords the corresponding phosphorus containing, tertiary allylic alcohols