1353579-43-7Relevant articles and documents
Total synthesis of camptothecin and SN-38
Yu, Shanbao,Huang, Qing-Qing,Luo, Yu,Lu, Wei
, p. 713 - 717 (2012/03/11)
A new practical and concise total synthesis of enantiopure camptothecin and SN-38 (14% overall yield, 99.9% ee and 99.9% purity) was described, starting from inexpensive and readily available materials. The development of column chromatography-free purification was achieved in all steps, which offers an economic industrial process to the camptothecin-family alkaloids.