1354828-74-2Relevant academic research and scientific papers
Synthesis of benzannulated heterocycles by twofold Suzuki-Miyaura couplings of cyclic diarylborinic acids
Dimitrijevic, Elena,Cusimano, Madeline,Taylor, Mark S.
, p. 1391 - 1394 (2014/03/21)
Two-fold Suzuki-Miyaura cross-couplings of cyclic diarylborinic acids are described. This novel annulation method enables the synthesis of benzo-fused heterocycles from dihaloarenes or gem-dibromoolefins.
Solar energy assisted synthesis of palladium nanoplates and its application in 2-phenoxy-1,1′-biphenyls and N,N-dimethyl-[1,1′-biphenyl] derivatives synthesis
Patil, Aniruddha B.,Bhanage, Bhalchandra M.
, p. 30 - 37 (2013/09/12)
Present work aims to develop a greener approach for the palladium nanoplates (PdNPs) synthesis and its catalytic applications. The protocol deals with solar energy assisted ionic palladium reduction in the presence of polyvinylpyrrolidone (PVP) and ethylene glycol (EG) with a good shape selectivity. Polyvinylpyrrolidone plays a duel role of capping agent and mild reductant; whereas, ethylene glycol acts as a reductant and solvent. The optimum sunlight concentration is a key factor to the anticipated nanoplate's synthesis. Results show that the most of nanoparticles are hexagonal and triangular nanoplates in the range of 20-50 nm. This is a first report which shows ～70% selectivity to the nanoplates formation using sun light. The study also covers it's catalytic application, wherein; 2-phenoxy-1,1′- biphenyls and N,N-dimethyl-[1,1′-biphenyl] derivatives were synthesized by a simple, ligand free, faster, one pot, ecological and economic protocol in aqueous medium. The catalyst shows better performance than that of conventionally available 10% Pd/C catalyst. The prepared PdNPs showed excellent catalytic performance to the desired products with recyclability.
Nucleophilic substitutions and radical reactions of phenylazocarboxylates
Jasch, Hannelore,Hoefling, Sarah B.,Heinrich, Markus R.
, p. 1520 - 1532 (2012/03/11)
tert-Butyl phenylazocarboxylates are versatile building blocks for synthetic organic chemistry. Nucleophilic substitutions of the benzene ring proceed with aromatic amines and alcohols under mild conditions. The attack of aliphatic amines may be directed to the aromatic core as well as to the carbonyl unit leading to azocarboxamides. The benzene ring can further be modified through radical reactions, in which the tert-butyloxycarbonylazo group enables the generation of aryl radicals at either elevated temperatures or under acidic conditions. Radical reactions include oxygenation, halogenation, carbohalogenation, carbohydroxylation, and aryl-aryl coupling.
