136053-34-4

Basic information

• Product Name: Silane, (1,1-dimethylethyl)(4-ethynylphenoxy)dimethyl-
• CAS NO: 136053-34-4
• Molecular Formula: C14H20OSi
• Molecular Weight: 232.398
• Mol File: 136053-34-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)(4-ethynylphenoxy)dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)(4-ethynylphenoxy)dimethyl-(136053-34-4)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)(4-ethynylphenoxy)dimethyl-(136053-34-4)

Safety Data

• Hazardous Substances Data: 136053-34-4(Hazardous Substances Data)

Upstream product

• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 1066-26-8 sodium acetylide 
• 133430-99-6 4-(tert-butyldimethylsilyloxy)iodobenzene 
• 88075-18-7 4-(2-(trimethylsilyl)ethynyl)phenol 
• 347377-08-6 tert-butyl(4-(2,2-dibromoethenyl)phenoxy)dimethylsilane 
• 123-08-0 4-hydroxy-benzaldehyde 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 
• 558-13-4 carbon tetrabromide 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 540-38-5 p-Iodophenol 
• 2200-91-1 4-ethynylphenol 
• 200625-51-0 [{4-(1,1-dimethylethyl)dimethylsiloxyphenyl}ethynyl]trimethylsilane 

Downstream Products

• 160549-25-7 (R)-(+)-4-(1-phenylethylcarbamoyl)phenylacetylene 
• 1310328-62-1 2-{6-[4-(tert-butyldimethylsilanyloxy)phenyl]-2,3-dihydrobenzo[1,2-b;5,4-b']difuran-2-yl}-propan-2-ol 
• 1310328-63-2 (R)-(-)-2-{6-[4-(tert-butyldimethylsilanyloxy)phenyl]-2,3-dihydrobenzo[1,2-b;5,4-b']difuran-2-yl}-propan-2-ol 
• 1310328-31-4 4-[6-(1-hydroxy-1-methylethyl)-5,6-dihydrobenzo[1,2-b;5,4-b']difuran-2-yl]phenol 
• 1310328-32-5 {4-[6-(1-hydroxy-1-methylethyl)-5,6-dihydrobenzo[1,2-b;5,4-b']difuran-2-yl]phenoxy}acetic acid ethyl ester 
• 1310328-64-3 (R)-(-)-4-[6-(1-hydroxy-1-methylethyl)-5,6-dihydrobenzo[1,2-b;5,4-b']difuran-2-yl]phenol 
• 1379804-78-0 1-(4-((tert-butyldimethylsilyl)oxy)phenyl)-5-phenylpent-1-yn-3-ol 
• 684216-71-5 1,3,5-tribromo-2,4,6-tris[p-(tert-butyldimethylsilyloxy)phenylethynyl]benzene 
• 684216-73-7 1-bromo-2,3,4,5,6-pentakis[p-(tert-butyldimethylsilyloxy)phenylethynyl]benzene 

Relevant articles and documents

Nickel-Catalyzed Decarbonylative Cycloaddition of Benzofuran-2,3-diones with Alkynes to Flavones

Using dppe as the ligand, the Nickel-catalyzed decarbonylative cycloaddition of benzofuran-2,3-diones with alkynes was established, and a variety of functional flavones were synthesized in 65–99% yields. Terminal alkynes with substituted phenyl groups and internal alkynes such as aryl acyl acetylenes and diphenylacetylenes are suitable for this reaction. The effects of bases on the reactions of different types of alkyne substrates were also investigated and discussed. (Figure presented.).

INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE

The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).

Synthesis, electrochemistry and anticancer activity of novel ferrocenyl phenols prepared via azide-alkyne 1,3-cycloaddition reaction

A series of monophenols and diphenols containing the ferrocene-C triazolyl and ferrocene-Ntriazolyl bond were prepared in a cycloaddition reaction of ethynylferrocene with aryl and benzyl azides and in a reaction of azidoferrocene with phenylacetylenes, respectively. The anticancer activity of the prepared compounds against hormone-dependent (MCF-7) and hormone-independent (HCC38) breast cancer cell lines was studied. The investigated compounds exhibited moderate anticancer activity against hormone-independent (IC50 ～ 15-48 μM) cancer cell line and low activity against hormone-dependent cancer cell line (IC50 ～ 84-98 μM).