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136122-46-8

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136122-46-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 136122-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,1,2 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136122-46:
(8*1)+(7*3)+(6*6)+(5*1)+(4*2)+(3*2)+(2*4)+(1*6)=98
98 % 10 = 8
So 136122-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H19Cl2N3O2/c1-19(2,9-17(25)26)8-16-23-15-7-14(21)10-22-18(15)24(16)11-12-3-5-13(20)6-4-12/h3-7,10H,8-9,11H2,1-2H3,(H,25,26)

136122-46-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[6-chloro-3-[(4-chlorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanoic acid

1.2 Other means of identification

Product number -
Other names MIPITROBAN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136122-46-8 SDS

136122-46-8Downstream Products

136122-46-8Relevant academic research and scientific papers

New Process for the Synthesis of Imidazopyridine Derivatives as Potent Orally Active Thromboxane A2 Receptor Antagonists

Nikolai, E.,Claude, S.,Teulon, J. M.

, p. 73 - 76 (2007/10/02)

A new synthetic route to prepare the 4-pyridin-2-yl>-3,3-dimethylbutanoic acid (UP 116-77) is described.UP 116-77 is a potent orally active TXA2/PGH2 receptor antagonist currently under pharmacological investigation.Its development needed a suitable synthesis for industrial processing.The cyclization of 3-amino-5-chloro-2-(4-chlorophenyl)methylaminopyridine 4 with 3,3-dimethylglutaric anhydride in refluxing acetic acid affords a new efficient and simple way to UP 116-77 and subsequently to various 2-substituted imidazopyridine derivatives.

Synthesis and Structure - Activity Relationships of Novel Benzimidazole and Imidazopyridine Acid Derivatives as Thromboxane A2 Receptor Antagonists

Nicolai, Eric,Goyard, Joel,Benchetrit, Thierry,Teulon, Jean-Marie,Caussade, Francois,et al.

, p. 1176 - 1187 (2007/10/02)

A series of 1-benzylbenzimidazole and 3-benzylimidazopyridine substituted in the 2-position by an alkanoic or mercaptoalkanoic acid chain was synthesized for evaluation as potential thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonists.T

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