1361960-39-5Relevant academic research and scientific papers
SnCl2-catalyzed propargylic substitution of propargylic alcohols with carbon and nitrogen nucleophiles
Masuyama, Yoshiro,Hayashi, Miki,Suzuki, Noriyuki
, p. 2914 - 2921 (2013)
A weak Lewis acid, tin(II) chloride, which is insensitive to water and air, functioned as a catalyst for the propargylic substitution of secondary propargylic alcohols with carbon nucleophiles, such as electron-rich arenes, heteroarenes, and 1,3-dicarbony
Transition-Metal-Catalyst-Free Cross-Coupling Reaction of Secondary Propargylic Acetates with Alkenyl- and Arylboronic Acids
Ueda, Mitsuhiro,Nakakoji, Daiki,Morisaki, Takahiro,Ryu, Ilhyong
supporting information, p. 7040 - 7045 (2017/12/28)
A cross-coupling reaction between secondary propargylic acetates and alkenylboronic acids proceeded to give 1,4-enynes in good yields without addition of transition metal catalyst and base. This simple protocol was also applicable to arylboronic acids, which gave 3-arylated alkynes in good yields. The observed induction period suggested that the reaction of propargylic acetates and organoboronic acids was affected by the in-situ generated AcOH as a catalyst, which was confirmed by a separate experiment.
Synthesis of allenes via gold-catalyzed intermolecular reaction of propargylic alcohols and aromatic compounds
Xu, Cheng-Fu,Xu, Mei,Yang, Liu-Qing,Li, Chuan-Ying
, p. 3010 - 3016 (2012/05/05)
Functionalized allenes are efficiently synthesized in moderate to high yield from gold-catalyzed intermolecular reaction of propargylic alcohols and aromatic compounds. The user-friendly process could be conducted under mild reaction conditions with easily accessible starting materials.
