136329-39-0 Usage
General Description
(R)-(-)-N-Methyl-1-phenyl-2-(1-pyrrolidino)ethylamine is a chemical compound with the molecular formula C14H20N2. It is an enantiomer of a psychoactive drug known as methamphetamine, which is a potent central nervous system stimulant. (R)-(-)-N-METHYL-1-PHENYL-2-(1-PYRROLIDINO)ETHYLAMINE has a chiral center and exists in two enantiomeric forms, with the (R)-(-)-enantiomer having stronger activity compared to the (S)-(+) enantiomer. It is sometimes used as a reference compound in studies involving other psychoactive substances, and its pharmacological effects are attributed to its ability to increase the release of dopamine and norepinephrine in the brain. However, it is important to note that this compound has potential for abuse and can have adverse effects on human health.
Check Digit Verification of cas no
The CAS Registry Mumber 136329-39-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,3,2 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 136329-39:
(8*1)+(7*3)+(6*6)+(5*3)+(4*2)+(3*9)+(2*3)+(1*9)=130
130 % 10 = 0
So 136329-39-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2/c1-14-13(11-15-9-5-6-10-15)12-7-3-2-4-8-12/h2-4,7-8,13-14H,5-6,9-11H2,1H3
136329-39-0Relevant articles and documents
A simple and efficient method for the preparation of homochiral amines: Application to the synthesis of a new C2 symmetric triamine
O'Brien, Peter,Poumellec, Pierre
, p. 5619 - 5622 (1996)
Using a one-pot reaction, (R)-styrene oxide has been converted into a variety of novel diamines and a C2 symmetric triamine. Yields range from 63-93%. The method is simple, efficient and is considerably shorter than other synthetic approaches.
Two useful methods for the preparation of (R)- and (S)-N-methyl-1-phenyl-2-(1-pyrrolidinyl)ethanamine
De Sousa, Simon E.,O'Brien, Peter,Poumellec, Pierre
, p. 2613 - 2618 (2007/10/03)
Two methods for the efficient preparation of either enantiomer of the synthetically useful diamine N-methyl-1-phenyl-2-(1-pyrrolidinyl)ethanamine are reported. Each of the methods starts from readily available materials (styrene oxide or phenylglycinol) a
Synthesis of Versatile Intermediates for Cyclopentanoid Natural Products via Enantioselective Deprotonation of Substituted Cyclopentene Oxide
Bhuniya, Debnath,Gupta, Arpita Datta,Singh, Vinod K.
, p. 2847 - 2850 (2007/10/02)
Enantioselective deprotonation of cis and trans-3,4-epoxycyclopentan-1-ol derivatives with phenylglycine based ligand (R)-5 was studied.The cyclopentanoid intermediates were obtained in a maximum of 88percent ee.
