1365546-07-1

Basic information

• Product Name: C₃₈H₄₄N₂O₅
• Synonyms: C₃₈H₄₄N₂O₅
• CAS NO: 1365546-07-1
• Molecular Weight: 608.778
• Mol File: 1365546-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₈H₄₄N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₈H₄₄N₂O₅(1365546-07-1)
• EPA Substance Registry System: C₃₈H₄₄N₂O₅(1365546-07-1)

Safety Data

• Hazardous Substances Data: 1365546-07-1(Hazardous Substances Data)

Upstream product

• 65136-52-9 4-(3-chloropropoxy)benzoic acid 
• 65136-48-3 4-(3-chloropropoxy)benzoic acid chloride 
• 526196-90-7 2-n-butyl-5-aminobenzofuran hydrochloride 
• 1365546-06-0 3-[4-(3-chloropropoxy)benzoyl]-2-n-butylbenzofuran-5-yl-1H-isoindole-1,3(2H)dione 
• 111-92-2 dibutylamine 
• 1365546-05-9 2-(-2-butyl-1-benzofuran-5-yl)-1H-isoindole-1,3(2H)dione 
• 85-44-9 phthalic anhydride 

Downstream Products

• 141644-91-9 (5-amino-2-butyl-benzofuran-3-yl)-[4-(3-dibutylamino-propoxy)-phenyl]-methanone 
• 500791-70-8 5-amino-2-n-butyl-3-[4-(3-di-n-butylamino propoxy)benzoyl]benzofuran bisoxalate 
• 141626-36-0 dronedarone 

Relevant articles and documents

An improved scalable route to pure dronedarone hydrochloride

An efficient scalable synthesis for dronedarone hydrochloride (2) via Friedel-Craft acylation of 2-(-2-butyl-1-benzofuran-5-yl)-1H-isoindole-1,3(2H) dione (12) with 4-(3-chloropropoxy) benzoic acid (13) in good yield and high purity has been developed by using Eaton's reagent instead of hazardous and toxic metal halide catalyst like AlCl3 or SnCl4.