65136-48-3Relevant articles and documents
The neuronal calcium ion channel activity of constrained analogues of MONIRO-1
Bispat, Anjie,Cardoso, Fernanda C.,Duggan, Peter J.,Geoffroy, Chloe,Lewis, Richard J.,Marliac, Marie-Adeline,Schmit, Matthieu,Tuck, Kellie L.
, (2020/07/28)
Structural modifications of the neuronal calcium channel blocker MONIRO-1, including constraining the phenoxyaniline portion of the molecule and replacing the guanidinium functionality with tertiary amines, led to compounds with significantly improved aff
Preparation and applications of phenylquinolinone-based and flavone-based derivative
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Paragraph 0023; 0044; 0047; 0048, (2019/01/10)
The present invention relates to a phenylquinolinone-based and flavone-based derivative and a preparation method thereof, wherein the derivative is a histamine H3 receptor antagonist, can protect andrestore the normal function of central nervous system, e
FUSED OXAZOLES and THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS
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Page/Page column 93-94, (2008/06/13)
The present invention relates to compounds comprising fused oxazole or thiazole derivatives of formula (I), processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, wherein A is a cyclic amine which is linked to the propylene group via an amino nitrogen; B is selected from the group consisting of heteroaryl, 5-8-membered heterocycloalkyl, 5-8-membered cycloalkyl; X is either N or CH; Y is either O or S.