136633-81-3Relevant articles and documents
CYCLIZATION REACTIONS OF NITRILES
Matrosova, S. V.,Zav'yalova, V. K.,Litvinov, V. P.,Sharanin, Yu. A.
, p. 1456 - 1459 (2007/10/02)
The interaction of 2-thienylidene derivatives of malononitrile and cyanothioacetamide with methylene active nitriles gives 2,6-diamino-3,5-dicyano-4-(2-thienyl)-4H-thiopyran which is smoothly recrystallized into 6-amino-3,5-dicyano-4-(2-thienyl)-2(1H)-pyridinethione.The latter is easily alkylated at the sulfur atom by α-halocarbonyl compounds.This reaction was used in the synthesis of 3,6-diamino-4-(2-thienyl)thienopyridines.