13682-29-6Relevant articles and documents
Ytterbium triflate as an efficient catalyst for one-pot synthesis of substituted imidazoles through three-component condensation of benzil, aldehydes and ammonium acetate
Wang, Li-Min,Wang, Yong-Hong,Tian, He,Yao, Yin-Fang,Shao, Jue-Hua,Liu, Bo
, p. 1570 - 1573 (2006)
Yb(OTf)3 has been found to be an extremely efficient catalyst for the preparation of imidazoles derivatives via three-component coupling reactions of benzil, aldehydes and ammonium acetate under mild conditions. The process presented here is op
Ytterbium perfluorooctanesulfonate as an efficient and recoverable catalyst for the synthesis of trisubstituted imidazoles
Shen, Ming-Gui,Cai, Chun,Yi, Wen-Bin
, p. 541 - 544 (2008)
Synthesis of trisubstituted imidazoles was successfully accomplished using rare earth(III) perfluorooctanesulfonates (RE(OPf)3), RE = Sc, Y, La-Lu as catalysts in fluorous solvents. Ytterbium perfluorooctanesulfonates (Yb(OPf)3) catalyze the high efficient synthesis of trisubstituted imidazoles in fluorous solvents. By simple separation, fluorous phase containing only catalyst can be reused several times.
A 2, 4, 5 - tri-substituted imidazole of preparation method (by machine translation)
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Paragraph 0048; 0049; 0050, (2019/04/10)
The invention relates to a 2, 4, 5 - tri-substituted imidazole of preparation method, the method is to be sequentially [...] or benzoins, aldehyde compounds, ammonium acetate and catalyst organic acid added in the reactor, in the 85 - 125 °C oil bath under the heating condition the reaction, after the reaction is complete to obtain a reaction mixture; the reaction mixture by washing, filtration, recrystallization after separation, to get the pure product 2, 4, 5 - tri-substituted imidazole. The present invention is simple, the production cost is low, and the yield is high, and has a good industrial application prospect. (by machine translation)
Synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in water using p-dodecylbenzenesulfonic acid as catalyst
Das, Biswanath,Kashanna, Jajula,Kumar, Rathod Aravind,Jangili, Paramesh
, p. 223 - 226 (2013/07/27)
2,4,5-Trisubstituted imidazoles have been synthesized by treatment of benzil with aldehydes and ammonium acetate in water under reflux in the presence of p-dodecylbenzenesulfonic acid as catalyst. The same reaction using an additional amine affords 1,2,4,