13691-26-4

Basic information

• Product Name: 1-(4-NITROPHENYL)-2-PYRROLIDINONE
• Synonyms: 1-(4-NITRO-PHENYL)-PYRROLIDIN-2-ONE;1-(4-Nitrophenyl)-2-pyrrolidinone,99+%;1-(4-nitrophenyl)-2-pyrrolidone;TIMTEC-BB SBB006388;1-(4-NITROPHENYL)-2-PYRROLIDINONE
• CAS NO: 13691-26-4
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.2
• Mol File: 13691-26-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: 128-130 °C
• Boiling Point: 345.04°C (rough estimate)
• Flash Point: 242.8 °C
• Appearance: brown-orange to brown crystalline powder
• Density: 1.2815 (rough estimate)
• Vapor Pressure: 2.71E-09mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: 2-8°C
• PKA: -3.84±0.20(Predicted)
• CAS DataBase Reference: 1-(4-NITROPHENYL)-2-PYRROLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-NITROPHENYL)-2-PYRROLIDINONE(13691-26-4)
• EPA Substance Registry System: 1-(4-NITROPHENYL)-2-PYRROLIDINONE(13691-26-4)

Safety Data

• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 13691-26-4(Hazardous Substances Data)

Usage

Chemical Properties

brown-orange to brown crystalline powder

InChI:InChI=1/C10H10N2O3/c13-10-2-1-7-11(10)8-3-5-9(6-4-8)12(14)15/h3-6H,1-2,7H2

Upstream product

• 14372-12-4 cyclopropanecarboxylic acid (4-nitrophenyl)amide 
• 616-45-5 2-pyrrolidinon 
• 636-98-6 p-nitrobenzene iodide 
• 350-46-9 4-Fluoronitrobenzene 
• 100-00-5 4-chlorobenzonitrile 
• 586-78-7 para-nitrophenyl bromide 
• 13691-22-0 1-(4-aminophenyl)pyrrolidin-2-one 
• 100-01-6 4-nitro-aniline 
• 58973-27-6 1-(4-nitrophenyl)pyrrolidine-2-thione 
• 82547-19-1 N-(4'-nitrophenyl)-4-chlorobutanamide 
• 87962-89-8 4-amino-N-(4-nitrophenyl)butanoic acid 
• 4641-57-0 1-phenylpyrrolidin-2-one 

Downstream Products

• 87962-93-4 1-(2,4-dinitro-phenyl)-pyrrolidin-2-one 
• 87962-89-8 4-amino-N-(4-nitrophenyl)butanoic acid 
• 58973-27-6 1-(4-nitrophenyl)pyrrolidine-2-thione 
• 1621326-32-6 (S)-3a-hydroxy-6-methyl-1-(4-nitrophenyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,3-b]quinolin-4-one 
• 10220-22-1 1-(4-nitro-phenyl)-pyrrolidine 
• 1621326-30-4 1-(4-nitrophenyl)-6-methyl-1H,2H,3H,4H,9H-pyrrolo[2,3-b]quinolin-4-one 
• 86147-74-2 4-(4-amino-anilino)-butyric acid 
• 10466-75-8 4-(2,4-dinitro-anilino)-butyric acid 
• 116614-83-6 methyl (Z)-(1-(4-nitrophenyl)-2-pyrrolidinylidene)-acetate 

Relevant articles and documents

A Facile Oxidation of Tertiary Amines to Lactams by Using Sodium Chlorite: Process Improvement by Precise pH Adjustment with CO 2

By using cheap and innocuous sodium chlorite, a series of tertiary amines have been oxidized to the corresponding lactams with good selectivity and high yield. In this method, neither transition-metal catalyst nor oxidant was used. In the oxidation step, the pH of the sodium chlorite was precisely adjusted to pH around 6 using CO2, such pH is a compromise between oxidative properties, chemical stability, and unwanted precipitation. In addition, buffer salts are not necessary, which allows this oxidation reaction to be performed under safe and environmentally benign conditions.

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs

(S)-Blebbistatin is a widely used research tool to study myosin II, an important regulator of many motility based diseases. Its potency is too low to be of clinical relevance, but identification of analogs with enhanced potency could deliver leads for tar

Cobalt-catalyzed intermolecular C(sp2)-O cross-coupling

Cobalt(II)-catalyzed C(sp2)-O cross-coupling between aryl/heteroaryl alcohols and vinyl/aryl halides in the presence of CuI has been achieved under ligand-free conditions. In this reaction, copper plays a significant role in transmetalation rather than being directly involved in the C-O coupling. This unique Co/Cu-dual catalyst system provides an easy access to a library of aryl-vinyl, heteroaryl-styryl, aryl-aryl, and heteroaryl-heteroaryl ethers in the absence of any ligand or additive.