13720-90-6Relevant articles and documents
Divergent Synthesis of Quinolones and Dihydroepindolidiones via Cu(I)-Catalyzed Cyclization of Anilines with Alkynes
Xu, Xuefeng,Sun, Ruzhong,Zhang, Sheng,Zhang, Xu,Yi, Wei
supporting information, p. 1893 - 1897 (2018/04/16)
A unique and efficient method for one-pot synthesis of diverse 4-quinolones from simple and readily available primary anilines and alkynes via Cu(I)-catalyzed direct cyclization has been developed. The (thio)phenols were also found to visible substrates for this reaction. Moreover, an unprecedented synthesis of dihydroepindolidiones has been demonstrated by using secondary anilines as the versatile substrates.
Facile synthesis of 4-quinolone derivatives via one-pot cascade reaction under transition-metal-free conditions
Huang, Chao,Guo, Jia-Hui,Fu, Huang-Mei,Yuan, Ming-Long,Yang, Li-Juan
, p. 3777 - 3781 (2015/06/08)
A practical and efficient strategy has been described for the preparation of 4-quinolone derivatives. Using commercially available diethyl acetylenedicarboxylate and aromatic amines as starting materials, the synthetic protocol has been achieved and affor
SYNTHETIC CONNECTIONS TO THE AROMATIC DIRECTED METALATION REACTION. A MODIFIED von NIEMENTOWSKI QUINOLINE SYNTHESIS FROM ANTHRANILAMIDES
Chong, R.J.,Siddiqui, M.A.,Snieckus, V.
, p. 5323 - 5326 (2007/10/02)
Anthranilamides 1, A = NR2 derived from benzamides by directed ortho metalationamination, are converted into the corresponding imines 4 which upon treatment with LDA lead to substituted 4-quinolones 5 thus providing a general new quinoline synthesis (Tabl