76854-95-0

Basic information

• Product Name: 2-AMINO-N,N-DIETHYLBENZAMIDE
• Synonyms: 2-AMINO-N,N-DIETHYLBENZAMIDE
• CAS NO: 76854-95-0
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.26
• Mol File: 76854-95-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 63-65 °C
• Boiling Point: 170 °C
• Appearance: /
• Density: 1.068±0.06 g/cm3(Predicted)
• PKA: 1.55±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-N,N-DIETHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N,N-DIETHYLBENZAMIDE(76854-95-0)
• EPA Substance Registry System: 2-AMINO-N,N-DIETHYLBENZAMIDE(76854-95-0)

Safety Data

• Hazardous Substances Data: 76854-95-0(Hazardous Substances Data)

Usage

Molecular Weight

229.31 g/mol

Derivative

Benzamide

Functional Groups

Amino group, two ethyl groups

Applications

Pharmaceuticals, organic synthesis

Usage

Building block for synthesizing new chemical compounds

Caution

Handle with care due to potential health and environmental hazards

Upstream product

• 1696-17-9 N,N-diethylbenzamide 
• 552-16-9 ortho-nitrobenzoic acid 
• 118-92-3 anthranilic acid 
• 610-14-0 2-nitrobenzyl chloride 
• 109-89-7 diethylamine 
• 21563-73-5 2-aminobenzoyl chloride 
• 361440-19-9 1-azido-2-(diethylaminomethyl)benzene 
• 10345-77-4 2-nitro-N,N-diethylbenzamide 
• 134-20-3 2-carbomethoxyaniline 
• 55668-30-9 2-aminobenzoic acid 2,5-dioxopyrrolidin-1-yl ester 
• 118-48-9 isatoic anhydride 

Downstream Products

• 57946-98-2 N,N-Diethyl-2-trifluoromethanesulfonylamino-benzamide 
• 109072-19-7 2-[(E)-2-Diethylcarbamoyl-phenylimino]-propionic acid ethyl ester 
• 109072-17-5 N,N-Diethyl-2-[1-methyl-hex-(E)-ylideneamino]-benzamide 
• 109072-20-0 N,N-Diethyl-2-[1-ethyl-but-(E)-ylideneamino]-benzamide 
• 138867-16-0 2-(2-fluorophenyl)quinazolin-4(3Η)-one 
• 83800-83-3 2-(4-(trifluoromethyl)phenyl)quinazolin-4(3Η)-one 
• 109072-21-1 2-Cyclohexylideneamino-N,N-diethyl-benzamide 
• 26059-80-3 2-cyclohexylquinazolin-4(3Η)-one 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 
• 109072-18-6 N,N-Diethyl-2-[1-phenyl-eth-(E)-ylideneamino]-benzamide 
• 1769-24-0 2-methyl-4-quinazolone 
• 198414-90-3 N₁,N₁-diethyl-2-[(phenylsulfonyl)amino]benzamide 
• 1222534-44-2 C₂₇H₃₂N₂O₃ 
• 1222534-45-3 C₂₇H₃₂N₂O 

Relevant articles and documents

Direct Hydroxylation and Amination of Arenes via Deprotonative Cupration

Deprotonative directed ortho cupration of aromatic/heteroaromatic C-H bond and subsequent oxidation with t-BuOOH furnished functionalized phenols in high yields with high regio- and chemoselectivity. DFT calculations revealed that this hydroxylation reaction proceeds via a copper (I → III → I) redox mechanism. Application of this reaction to aromatic C-H amination using BnONH2 efficiently afforded the corresponding primary anilines. These reactions show broad scope and good functional group compatibility. Catalytic versions of these transformations are also demonstrated.

Synthesis, antimicrobial evaluation, ot-QSAR and mt-QSAR studies of 2-amino benzoic acid derivatives

A series of 2-amino benzoic acid derivatives (1-28) were synthesized and evaluated for their in vitro antimicrobial activity against the panel of Gram positive, Gram negative bacterial and fungal strains. The results of antimicrobial studies indicated that, in general, the synthesized compounds were found to be bacteriostatic and fungistatic in action. QSAR studies performed by the development of one target and multi target models indicated that multi-target model was effective in describing the antimicrobial activity as well demonstrated the effect of structural parameters viz. LUMO, 3χv and W on antimicrobial activity of 2-amino benzoic acid derivatives. Springer Science+Business Media, LLC 2010.

Design, synthesis and biological evaluation of substituted dioxodibenzothiazepines and dibenzocycloheptanes as farnesyltransferase inhibitors

A new series of FTase inhibitors containing a tricyclic moiety-dioxodibenzothiazepine or dibenzocycloheptane-has been designed and synthesized. Among them, dioxodibenzothiazepine 18d displayed significant inhibitory FTase activity (IC50 = 17.3