13727-29-2Relevant academic research and scientific papers
Synthesis of alicyclic N-substituted 1,3-amino alcohols via 1,3-oxazines
Balazs, Arpad,Szakonyi, Zsolt,Fueloep, Ferenc
, p. 403 - 406 (2008/03/29)
(Chemical Equation Presented) Alicyclic N-substituted 1,3-amino alcohols 13-18 were prepared in a facile way in a one-pot procedure from 1,3-oxazines 5-8 in the presence of a ketone 9-12. The complex reaction involves palladium-catalyzed reduction, debenz
A Facile Preparation of N-(Isopropoxyalkyl) Amides by Generation and Trapping of N-Acyliminium Ions from Ionization-Rearrangement Reactions of N-Triflyloxy Amides
Hoffman, Robert V.,Nayyar, Naresh K.
, p. 3530 - 3539 (2007/10/02)
A series of hydroxamic acids were converted to N-triflyloxy amides which were heated in 2-propanol to give N-(1-isopropoxyalkyl) amides in high yields.The method is simple, direct, and extremely tolerant of structural diversity both in the N-acyl group, a
Generation of N-Acyl Iminium Ions from Ionization-Rearrangement Reactions of N-Triflyloxy Amides
Hoffman, Robert V.,Nayyar, Naresh K.,Shankweiler, Jean M.,Klinekole III, Bruce W.
, p. 3231 - 3234 (2007/10/02)
N-Triflyloxy amides undergo ionization in refluxing isopropanol to give N-acyliminium ions which can be trapped by addition of allyltrimethylsilane to the reaction mixture.Alternatively they can be converted to N-(isopropoxy)alkyl amides and then back to
Synthesis and some transformations of substituted 5,6-dihydro-4H-1,3-oxazines
Katritzky, Alan R.,Shcherbakova, Irina V.,Tack, Robert D.,Dai, Xue-Qian
, p. 3907 - 3918 (2007/10/02)
Substituted 5,6-dihydro-4H-1,3-oxazines are prepared by the acid-catalyzed amidoalkylation of the terminal olefins. 5,6-Dihydro-4H-oxazines undergo further transformations involving the hetero-ring and/or the substituent leading to alkyl amino-substituted
STEREOCHEMICAL STUDIES, 80. CYCLIC AMINOALCOHOLS AND RELATED COMPOUNDS, 26. PREPARATION OF CIS-2-(ALKYLAMINOMETHYL)- AND (ARALKYLAMINOMETHYL)-1-CYCLANOLS FROM OLEFINS VIA THE 5,6-DIHYDRO-4H-1,3-OXAZINE DERIVATIVES
Simon, Lajos,Talpas, Gizella S.,Fueloep, Ferenc,Bernath, Gabor
, p. 139 - 146 (2007/10/02)
Cycloalkenes were allowed to react with N-(hydroxymethyl)alkyl- or -arylamides in the presence of concentrated sulfuric acid in glacial acetic acid, using the method suggested by Schmidt.In the majority of cases, the reaction yielded the corresponding cis
