1373319-41-5

Basic information

• Product Name: methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate
• Synonyms: methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate
• CAS NO: 1373319-41-5
• Molecular Weight: 594.621
• Mol File: 1373319-41-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate(1373319-41-5)
• EPA Substance Registry System: methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate(1373319-41-5)

Safety Data

• Hazardous Substances Data: 1373319-41-5(Hazardous Substances Data)

Upstream product

• 681465-85-0 4-amino-3-isopropoxybenzoic acid methyl ester 
• 186413-80-9 2-isopropoxy-3-nitro-6-vinylpyridine 
• 186413-77-4 6-chloro-3-nitro-2-(propan-2-yloxy)pyridine 
• 379261-85-5 3-(isopropyloxy)-4-nitrobenzoic acid 
• 713-52-0 methyl 3-hydroxy-4-nitrobenzoate 
• 619-14-7 3-hydroxy-4-nitro-benzoic acid 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 159783-41-2 methyl 3-isopropyloxy-4-nitrobenzoate 
• 1006030-92-7 methyl 3-isopropoxy-4-(3-isopropoxy-4-amino-benzoylamino)-benzoate 
• 186413-90-1 6-isopropoxy-5-nitropyridine-2-carboxylic acid 
• 1006030-83-6 methyl 3-isopropoxy-4-(3-isopropoxy-4-nitro-benzoylamino)-benzoate 

Downstream Products

• 1373319-45-9 methyl 4-(4-(5-amino-6-isopropoxypicolinamido)-3-isopropoxybenzamido)-3-isopropoxybenzoate 
• 1373319-33-5 4-(4-(5-amino-6-isopropoxypicolinamido)-3-isopropoxybenzamido)-3-isopropoxybenzoic acid 

Relevant articles and documents

Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: Identification of potent Bcl-xL inhibitors

By conducting a structure-activity relationship study of the backbone of a series of oligoamide-foldamer-based α-helix mimetics of the Bak BH3 helix, we have identified especially potent inhibitors of Bcl-xL. The most potent compound has a Ki value of 94 nM in vitro, and single-digit micromolar IC50 values against the proliferation of several Bcl-xL-overexpressing cancer cell lines. The Royal Society of Chemistry 2012.