137634-62-9

Basic information

• Product Name: 4-methyl-2-phenethylquinoline
• Synonyms: 4-methyl-2-phenethylquinoline
• CAS NO: 137634-62-9
• Molecular Weight: 247.34
• Mol File: 137634-62-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4-methyl-2-phenethylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-phenethylquinoline(137634-62-9)
• EPA Substance Registry System: 4-methyl-2-phenethylquinoline(137634-62-9)

Safety Data

• Hazardous Substances Data: 137634-62-9(Hazardous Substances Data)

Upstream product

• 143671-61-8 4-methylquinoline trifluoroacetate 
• 589-10-6 phenoxyethyl bromide 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 501-52-0 3-Phenylpropionic acid 
• 113779-53-6 iodobenzene di(3-phenylpropanoate) 
• 137634-59-4 2-Phenylethyl hydrogen oxalate 
• 34420-17-2 (2-phenylethyl)boronic acid 
• 122-78-1 phenylacetaldehyde 
• 100-52-7 benzaldehyde 
• 19343-79-4 2,4-dimethyl-1,2,3,4-tetrahydroquinoline 
• 60-12-8 2-phenylethanol 
• 7304-91-8 diphenylselenoxide 

Relevant articles and documents

Rh(III)-Catalyzed Chemoselective C-H Alkenylation and [5 + 1] Annulation with Gem-Difluoromethylene Enabled by the Distinctive Fluorine Effect

The efficient couplings of diverse N-arylureas and gem-difluoromethylene alkynes have been realized via Rh(III)-catalyzed chemoselective C-H alkenylation and [5 + 1] annulation, which were induced by the distinctive fluorine effect to provide the different coordination mode of the Rh(III) catalyst binding to the directing group, thereby giving the direct access to difluorinated 2-alkenyl arylureas and 3,4-dihydroquinazolin-2(1H)-ones bearing both an α-quaternary carbon center and a monofluoroalkenyl moiety with broad substrate compatibility and good functional group tolerance. The synthetic application in C-H alkenylation of the N-pyridylaniline, the late-stage [3 + 2] annulation, and the derivation of the obtained products has been also demonstrated to further strengthen the synthetic utility of the chemodivergent transformations.

Visible-light-mediated photoredox minisci C-H alkylation with alkyl boronic acids using molecular oxygen as an oxidant

Herein, we report a protocol for direct visible-light-mediated Minisci C-H alkylation reactions of heteroarenes with alkyl boronic acids using molecular oxygen as the sole oxidant. This mild protocol uses an inexpensive, green oxidant; permits efficient functionalization of various N-heteroarenes with a broad range of primary and secondary alkyl boronic acids; and is scalable to the gram level. We demonstrated the practicality and sustainability of the protocol by preparing or functionalizing several pharmaceuticals and natural products.

Photoelectrochemical C?H Alkylation of Heteroarenes with Organotrifluoroborates

A photoelectrochemical method for the C?H alkylation of heteroarenes with organotrifluoroborates has been developed. The merger of electrocatalysis and photoredox catalysis provides a chemical oxidant-free approach for the generation and functionalization