1377578-81-8Relevant articles and documents
Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes
Sharma, Hayden A.,Todd Hovey,Scheidt, Karl A.
, p. 9283 - 9286 (2016/07/25)
A convergent, transition-metal-free synthesis of 2-aryl-azaindoles has been developed. The interception of a reactive aza-ortho-azaquinone methide intermediate by an acyl anion equivalent generated through carbene catalysis provides high yields, a wide substrate scope, and the synthesis of previously inaccessible azaindoles.