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Upstream product

• 2045-75-2 3,3,5-trimethyl-3,4-dihydro-2H-pyrrole 
• 6931-11-9 2,4,4-trimethyl-1-pyrroline N-oxide 
• 73604-46-3 2,2-dimethyl-1-amino-pent-4-ene 
• 35223-73-5 4,4-dimethyl-5-nitropentan-2-one 
• 101861-91-0 4,4-ethylenedioxy-2,2-dimethyl-1-nitropentane 
• 54408-36-5 2,4,4-trimethylpyrrolidine-1-ol 
• 2978-30-5 2,2-dimethylpent-4-enenitrile 
• 7647-01-0 hydrogenchloride 

Relevant academic research and scientific papers

Donor ligand effects in group 3 metal-catalyzed hydroaminations

A series of donor ligands were examined for their effect on group 3 metal-catalyzed intramolecular alkene hydroamination. The cyclization proved to be surprisingly tolerant to the presence of several coordinative functional groups suggesting more latitude

Bis(amidinate) ligands in early lanthanide chemistry - synthesis, structures, and hydroamination catalysis

Bis(amidinate) ligands attached to rigid dibenzofuran and phenanthrene backbones have been introduced into lanthanide chemistry for the first time. Depending on the ligand and on the lanthanide source, either bi- and tetra-metallic macrocycles or monometa

Half-sandwich indenyl rare earth metal dialkyl complexes: Syntheses, structures, and catalytic activities of (1,3-(SiMe3) 2C9H5)Ln(CH2SiMe3) 2(THF)

Reactions of l,3-bis(trimethylsilyl)indene with Ln(CH2SiMe 3)3(THF)2 gave half-sandwich rare earth metal complexes (l,3-(SiMe3)2C9H5) Ln(CH2SiMe3

Investigating a Redox Active Samarium Complex in Catalytic Reactions

Herein the synthesis of a new ethynyl ferrocenyl amidinate ligand [Fc?C≡C-{C(Ndipp)2H}] (Fc=ferrocenyl; dipp=diisopropylphenyl) and the subsequent formation of the corresponding samarium amido complex [Sm{Fc?C≡C-[C(Ndipp)2]}2/s

Intramolecular hydroamination/cyclization of aminoalkenes catalyzed by diamidobinaphthyl magnesium- and zinc-complexes

Reaction of 2 equiv of n-Bu2Mg and Et2Zn with the chiral l-proline-derived axial chiral tetraamines (S,S,S)-1 and (R,S,S)-1 gave the chiral bimetallic complexes [M2{(S,S,S)-DABN(MeProline)2}{R}2] (M=Mg, R=n-Bu ((S,S,S)-2); M=Zn, R=Et ((S,S,S)-3)) and [M2{(R,S,S)-DABN(MeProline)2}{R}2] (M=Mg, R=n-Bu ((R,S,S)-2)); M=Zn, R=Et ((R,S,S)-3)). The magnesium complexes showed moderate to high catalytic activity in the intramolecular hydroamination/cyclization of aminoalkenes, though enantiomeric excess was limited to 14% ee due to protolytic ligand exchange processes. The zinc complexes were less reactive and generally required higher reaction temperatures of 60-100 °C, but achieved slightly higher enantiomeric excess of up to 29% ee.

Cyclopentadienylphosphazene (CpPN) complexes of rare-earth metals: Synthesis, structural characterization, and hydroamination catalysis

Synthesis of the first series of rare-earth-metal constrained geometry complexes containing the P-(1-adamantylamino)-P-dimethyl-tetramethyl- cyclopentadienylidene-phosphorane ligand C5Me4PMe 2NHAd, {Cp#PN}H, was

Mechanism of catalytic cyclohydroamination by zirconium salicyloxazoline complexes

The mechanism of hydroamination/cyclization of primary aminoalkenes by catalysts based on Cp*LZr(NMe2)2 (L = κ2-salicyloxazoline) is investigated in a range of kinetic, stoichiometric, and structural studies. The rate law

Neutral versus cationic Group 3 metal alkyl catalysts: Performance in intramolecular hydroamination/cyclisation

The relative catalytic activity of neutral dialkyl versus cationic monoalkyl Group 3 metal catalysts in the intramolecular hydroamination/ cyclisation of the 2,2-dimethyl-4-pentenylamine reference substrate was investigated. This was found to depend strongly on the nature of the monoanionic ancillary ligand. With a bidentate amidinate ligand, the neutral catalysts were quite effective, but their cationic derivatives showed a much lower activity. The reaction kinetics suggest that this reflects an intrinsically higher activation barrier for the insertion of the olefinic moiety into the metal-amide bond for the cationic catalysts. In contrast, the neutral catalysts with tetradentate triamine-amide ligands showed a much lower activity than their cationic derivatives. It appears that this higher activity of the cationic triamine-amide catalysts reflects the beneficial effect of the additional available coordination space relative to the neutral species. The cationic triamine-amide yttrium catalysts are more active than the cationic amidinate catalysts of the same metal, possibly reflecting a stronger Y-amide bond in the latter, which is the more electron-deficient system. The Royal Society of Chemistry 2006.

Highly fluorinated tris(indazolyl)borate silylamido complexes of the heavier alkaline earth metals: Synthesis, characterization, and efficient catalytic intramolecular hydroamination

Heteroleptic silylamido complexes of the heavier alkaline earth elements calcium and strontium containing the highly fluorinated 3-phenyl hydrotris(indazolyl)borate {F12-Tp4Bo,3Ph}- ligand have been synthesized by using salt metathesis reactions. The homoleptic precursors [Ae{N-(SiMe3)2}2] (Ae=Ca, Sr) were treated with [Tl(F12-Tp4Bo,3Ph)] in pentane to form the corresponding heteroleptic complexes [(F12-Tp4Bo,3Ph)Ae{N(SiMe3)2}] (Ae=Ca (1); Sr (3)). Compounds 1 and 3 are inert towards intermolecular redistribution. The molecular structures of 1 and 3 have been determined by using X-ray diffraction. Compound 3 exhibits a Sr...MeSi agostic distortion. The synthesis of the homoleptic THF-free compound [Ca{N(SiMe2H)2}2] (4) by transamination reaction between [Ca{N(SiMe3)2}2] and HN(SiMe2H)2 is also reported. This precursor constitutes a convenient starting material for the subsequent preparation of the THF-free complex [(F12-Tp4Bo,3Ph)Ca{N(SiMe2H)2}] (5). Compound 5 is stabilized in the solid state by a Ca...β-Si-H agostic interaction. Complexes 1 and 3 have been used as precatalysts for the intramolecular hydroamination of 2,2-dimethylpent-4-en-1-amine. Compound 1 is highly active, converting completely 200 equivalents of aminoalkene in 16 min with 0.50 mol% catalyst loading at 25°C.

Intramolecular hydroamination of aminoalkenes using rhodium(I) and Iridium(I) complexes with N,N-and P,N-donor ligands

Cationic rhodium(i) and iridium(i) complexes containing the bidentate heterocyclic N,N-donor ligand bis(1-pyrazolyl)methane (bpm) and the counterion tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (BArF-) were found to be efficient catalysts for the cycliz