1383536-75-1Relevant academic research and scientific papers
Tri(o-tolyl)phosphine for highly efficient Suzuki coupling of propargylic carbonates with boronic acids
Xiao, Junzhe,Luo, Hongwen,Huang, Shan,Qian, Hui,Ma, Shengming
supporting information, p. 10451 - 10454 (2018/09/22)
A highly efficient catalytic system consisting of Pd2(dba)3·CHCl3 and tri(o-tolyl)phosphine has been identified for the coupling of propargylic carbonates with different types of organo boronic acids at room temperature. Excellent central-to-axial chirality transfer was also demonstrated.
Highly efficient synthesis of allenes from trimethylaluminum reagent and propargyl acetates mediated by a palladium catalyst
Li, Qing-Han,Jeng, Jung-Yuan,Gau, Han-Mou
, p. 7916 - 7923 (2015/02/02)
A series of propargyl acetates were prepared and used as propargyl electrophiles for coupling reactions with trimethylaluminum. The simple catalytic system of palladium(II) acetate (1 mol-%) and tri(o-tolyl)phosphine (2 mol-%) worked efficiently for a wide variety of aromatic and aliphatic propargyl acetates, producing the substituted allenes in good to excellent yields of up to 94% in tetrahydrofuran. The process was simple and easily performed, and it provides an efficient method for the synthesis of substituted allene derivatives. On the basis of the experimental results, a possible catalytic cycle has been proposed.
Gold-catalyzed isomerization of unactivated allenes into 1,3-dienes under ambient conditions
Ting, Chun-Ming,Hsu, Yi-Ling,Liu, Rai-Shung
, p. 6577 - 6579 (2012/07/31)
We have developed a gold-catalyzed isomerization of unactivated allenes into 1,3-dienes with nitrosobenzene as an additive. This reaction proceeded almost exclusively at room temperature for highly substituted allenes. The utility of this reaction is manifested by the development of one-pot [4+2]-cycloaddition of allenes and reactive alkenes.
