1383658-29-4

Basic information

• Product Name: 3-(4-fluorophenyl)cyclobut-2-en-1-one
• Synonyms: 3-(4-fluorophenyl)cyclobut-2-en-1-one
• CAS NO: 1383658-29-4
• Molecular Weight: 162.163
• Mol File: 1383658-29-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)cyclobut-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)cyclobut-2-en-1-one(1383658-29-4)
• EPA Substance Registry System: 3-(4-fluorophenyl)cyclobut-2-en-1-one(1383658-29-4)

Safety Data

• Hazardous Substances Data: 1383658-29-4(Hazardous Substances Data)

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 130995-12-9 1-(4-fluorophenyl)-2-trimethylsilylacetylene 
• 1029080-42-9 2,2-dichloro-3-(4-fluorophenyl)cyclobutanone 

Downstream Products

• 1383658-46-5 C₁₄H₁₃FN₂O₃ 
• 1383658-37-4 C₁₄H₁₃FN₂O₃ 

Relevant articles and documents

Synthesis of Silylated Cyclobutanone and Cyclobutene Derivatives Involving 1,4-Addition of Zinc-Based Silicon Nucleophiles

A copper-catalyzed conjugate silylation of various cyclobutenone derivatives with Me2PhSiZnCl ? 2LiCl or (Me2PhSi)2Zn ? xLiCl (x≤4) to generate β-silylated cyclobutanones is reported. Trapping the intermediate enolate with ClP(O)(OPh)2 affords silylated enol phosphates that can be further engaged in Kumada cross-coupling reactions to yield silylated cyclobutene derivatives.

Enantioselective Synthesis of 4-Hydroxy-dihydrocoumarins via Catalytic Ring Opening/Cycloaddition of Cyclobutenones

A highly diastereo- and enantioselective ring-opening/cycloaddition reaction of cyclobutenones with 2-hydroxyacetophenones or salicylaldehyde was achieved by employing a chiral N,N′-dioxide-scandium(III) complex as the catalyst. It provided various 3-phen