139377-33-6Relevant articles and documents
Efficient synthesis of 1-Benzyloxyphenyl-3-phenylacetones
Mannekens,Tourwe,Lubell
, p. 1214 - 1216 (2000)
1-[(Benzyloxy)phenyl]-3-phenylacetones 1a-c have been conveniently synthesized by acylation of the PhCH2Li-DABCO complex with their respective N-methyl O-methyl hydroxamates 5a-c. In four steps, ketones 1a-c having ortho-, meta- and para-benzyloxy substituents were obtained in 42-51% overall yields from commercially available 2-(hydroxyphenyl)acetic acids.
BETA-LACTAMASE INHIBITORS
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Page/Page column 73, (2009/06/27)
Disclosed herein are alpha-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising alpha-aminoboronic acids and methods of use thereof.
Compounds and methods for modulation of estrogen receptors
-
, (2008/06/13)
Compounds that modulate the estrogen receptor (ER) are disclosed, as well as pharmaceutical compositions containing the same. In a specific embodiment, the compounds are selective for ER-β over ER-α. Methods are disclosed for modulating ER-β in cell and/o