1393902-40-3Relevant academic research and scientific papers
Synthesis of lamellarin R, lukianol A, lamellarin O and their analogues
Liou, Teau-Jiuan,Satyanarayana, Iddum,Yang, Ding-Yah
, p. 43168 - 43174 (2020/12/18)
Three lamellarin alkaloids type III (lamellarin R, lukianol A and lamellarin O) were synthesized using the Barton-Zard reaction as a key step to construct the central pyrrole core. Some of their corresponding 4-benzoyl and 5-phenyl substituted pyrrole ana
Method for synthesizing nitrogen-containing five-membered heterocyclic compound through reaction of three components under catalysis of iodine
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Paragraph 0097; 0098; 0141-0144, (2019/11/04)
The invention discloses a method for synthesizing a nitrogen-containing five-membered heterocyclic compound through a reaction of three components under the catalysis of iodine. The nitrogen-containing five-membered heterocyclic compound is a tetrahydropy
Domino transformation of isoxazoles to 2,4-dicarbonylpyrroles under Fe/Ni relay catalysis
Galenko, Ekaterina E.,Galenko, Alexey V.,Khlebnikov, Alexander F.,Novikov, Mikhail S.
, p. 18172 - 18176 (2015/05/12)
The domino reaction of 5-alkoxy- or 5-aminoisoxazoles, under metal relay catalysis, with symmetric 1,3-diketones gives 4-acylpyrrole-2-carboxylic acid derivatives in high yield. Esters and amides of acylacetic acids react regioselectively, giving derivati
Ambivalent role of metal chlorides in ring opening reactions of 2H-azirines: Synthesis of imidazoles, pyrroles and pyrrolinones
Auricchio, Sergio,Truscello, Ada M.,Lauria, Mirvana,Meille, Stefano V.
experimental part, p. 7441 - 7449 (2012/09/22)
2H-Azirines were found to react with imines, enaminones and enaminoesters in the presence of metal salts. Imidazoles, pyrroles and new pyrrolinones derivatives are isolated in good overall yields. The role of metal salts was investigated as they can act as Lewis acids or electron donors. Mechanisms are proposed suggesting that imidazoles arise from addition of azirine to imines via radical or ionic mechanism; pyrroles and pyrrolinones are obtained from azirines with enamino derivatives when the salt acts as a Lewis acid. In the latter case the properties of the metallic compound influence the reaction regioselectivity.
