1399176-09-0

Basic information

• Product Name: 4-(1-(5-(5-(azetidin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile
• Synonyms: 4-(1-(5-(5-(azetidin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile
• CAS NO: 1399176-09-0
• Molecular Weight: 490.608
• Mol File: 1399176-09-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(1-(5-(5-(azetidin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-(5-(5-(azetidin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile(1399176-09-0)
• EPA Substance Registry System: 4-(1-(5-(5-(azetidin-1-yl)-1H-imidazo[4,5-b]pyridin-2-yl)-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile(1399176-09-0)

Safety Data

• Hazardous Substances Data: 1399176-09-0(Hazardous Substances Data)

Upstream product

• 742081-03-4 5-iodo-2,4-dimethylbenzoic acid 
• 1399181-27-1 4-(1-(5-formyl-2,4-dimethylbenzoyl)piperidin-4-yl)benzonitrile 
• 589-87-7 1,4-bromoiodobenzene 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 163209-96-9 tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate 
• 871112-38-8 tert-butyl 4-(4-cyanophenyl)-4-hydroxypiperidine-1-carboxylate 
• 27048-04-0 2-amino-6-chloro-3-nitropyridine 
• 460365-08-6 4-(4-cyanophenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 162997-33-3 tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate 
• 162997-34-4 4-(piperidin-4-yl)benzonitrile hydrochloride 
• 611-01-8 2,4-dimethyl-benzoic acid 

Relevant articles and documents

TCNE-decorated triphenylamine-based conjugated polymer: Click synthesis and efficient turn-on fluorescent probing for Hg2+

A type of triphenylamine-based conjugated polymer with cyano-containing chromophore in side chain, poly[(9,9-dioctyl)-2,7-fluorene-co-N-4-(1,1,4,4- tetracyanobuta-1,3-dienyl)-4,4′-triphenylamine] (P3) was successfully synthesized by catalyst-free and efficient click reaction between poly[(9,9-dioctyl)-2,7-fluorene-co-N-4-ethynyl-4,4′-triphenylamine] (P2) and tetracyanoethylene (TCNE). Chemical structures of intermediates and target polymer were verified by FT-IR and 1H NMR analyses. Fluorescence of P3's THF solution was specifically quenched by the introduction of I -, accompanied by the change of its apparent color from pale brown to light yellow. With the introduction of Hg2+, fluorescence of P3/I- complex recovered quickly and even exceeded the initial intensity of pristine P3 (when the concentration of Hg2+ above ～6.65 × 10-5 M). Other common cations brought very slight interference for P3/I- complex's response of Hg2+, and the detection limit of Hg2+ reached ～6.9 nM for such probing system.2013 Elsevier Ltd. All rights reserved.

HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS

Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are