139962-69-9Relevant academic research and scientific papers
Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes
Sharma, Hayden A.,Todd Hovey,Scheidt, Karl A.
, p. 9283 - 9286 (2016)
A convergent, transition-metal-free synthesis of 2-aryl-azaindoles has been developed. The interception of a reactive aza-ortho-azaquinone methide intermediate by an acyl anion equivalent generated through carbene catalysis provides high yields, a wide substrate scope, and the synthesis of previously inaccessible azaindoles.
Reactions of β-(lithiomethyl)azines with nitriles as a route to pyrrolo-pyridines, - quinolines, -pyrazines, - quinoxalines and -pyrimidines
Davis, Michael L.,Wakefield, Basil J.,Wardell, Jacklyn A.
, p. 939 - 952 (2007/10/02)
Deprotonation of 3-methylazines, followed by reaction with benzonitile, gives an intermediate which, on treatment with additional strong base, cyclises to give 2-phenyl[1H]-pyrrolo[2,3-b]pyridine. The application of this type of reaction to a variety of n
