14004-47-8Relevant academic research and scientific papers
A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production
Che, Haiyan,Lim, Hyun,Kim, Hyun Pyo,Park, Haeil
experimental part, p. 4657 - 4660 (2011/11/07)
A number of 8-substituted chrysin analogs have been prepared and evaluated for their inhibitory activities of cyclooxygenase-2 catalyzed prostaglandin E2 and iNOS-mediated NO production. Analogs were prepared via Suzuki-Miyaura C-C cross coupli
Anti-AIDS agents 68. The first total synthesis of a unique potent anti-HIV chalcone from genus Desmos
Nakagawa-Goto, Kyoko,Lee, Kuo-Hsiung
, p. 8263 - 8266 (2007/10/03)
The first total synthesis of a unique highly functionalized and potent anti-HIV chalcone 1, isolated from genus Desmos, was achieved from commercially available 2,4,6-trihydroxytoluene (3) or 2,4,6-trihydroxybenzaldehyde (2) in five (from 3) or six steps (from 2).
Synthesis of (+)-(R)-5-hydroxy-6-hydroxymethyl-7-methoxy-8-methylflavanone
Solladie, Guy,Gehrold, Nicolai,Maignan, Jean
, p. 2739 - 2747 (2007/10/03)
The synthesis of (+)-(R)-5-hydroxy-6-hydroxymethyl-7-methoxy-8-methylflavanone is described. A new chromylation method of β-ketosulfoxide 9 leading to the Michael acceptor 12 has been developed. Dilithium tetra-chlorocuprate was shown to be a very efficie
