1400583-12-1

Basic information

• Product Name: Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester
• Synonyms: Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester;METHYL 3-((TERT-BUTOXYCARBONYL)AMINO)CYCLOPENTANE-1-CARBOXYLATE
• CAS NO: 1400583-12-1
• Molecular Formula: C12H21NO4
• Molecular Weight: 243.29944
• Mol File: 1400583-12-1.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester(1400583-12-1)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester(1400583-12-1)

Safety Data

• Hazardous Substances Data: 1400583-12-1(Hazardous Substances Data)

Usage

General Description

Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester is a chemical compound that is commonly used in the pharmaceutical industry as a building block for the synthesis of various drug molecules. It is a methyl ester derivative of cyclopentanecarboxylic acid, containing an amino group and a diMethylethoxy carbonyl group. Cyclopentanecarboxylic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester has the potential to be used in the development of new medications due to its structural properties and reactivity. It is important to handle and use this chemical with caution and follow proper safety protocols to prevent any adverse effects on human health and the environment.

Upstream product

• 67-56-1 methanol 
• 489446-85-7 (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 693245-53-3 tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate 
• 124-41-4 sodium methylate 
• 200002-41-1 (-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate] 
• 24424-99-5 di-tert-butyl dicarbonate 
• 130931-83-8 (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one 
• 74-88-4 methyl iodide 
• 261165-05-3 (1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid 
• 1085842-51-8 methyl (1S,3S)-3-aminocyclopentane-1-carboxylate hydrochloride 
• 168683-02-1 (1S,4R)-(-)-methyl-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopent-2-ene-1-carboxylate 
• 229613-83-6 (–)-methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate hydrochloride 
• 251327-00-1 methyl (4S)-4-[(tert-butyloxycarbonyl)amino]cyclopent-1-ene-1-carboxylate 

Downstream Products

• 489446-72-2 (1R,3R)-3-tert-butoxycarbonylaminocyclopentanecarboxylic acid methyl ester 
• 167081-31-4 ((1S,3S)-3-hydroxymethylcyclopentyl)carbamic acid tert-butyl ester 
• 180323-49-3 (1S,3R)-methyl 3-aminocyclopentanecarboxylate hydrochloride 

Relevant articles and documents

Highly selective directed hydrogenation of enantiopure 4-(tert-butoxycarbonylamino)cyclopent-1-enecarboxylic acid methyl esters

The use of both N-tert-butoxycarbonylamino- and hydroxyl-directed hydrogenation methodology to yield essentially single diastereomers of 3-(tert-butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl esters and 3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid methyl esters is described. These results incorporate the first reported carbamate-directed hydrogenations of functionalised cyclopentenes.

PYRAZOLO-PYRIMIDIN-AMINO-CYCLOALKYL COMPOUNDS AND THEIR THERAPEUTIC USES

Disclosed herein are pyrazolo-pyrimid in-ami no-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.

COMPLEMENT PATHWAY MODULATORS AND USES THEREOF

The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.