84531-36-2

Basic information

• Product Name: 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE
• Synonyms: 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE;3-nitro-5H,6H,7H-cyclopenta[b]pyridine;6,7-dihydro-3-nitro-5H-Cyclopenta[b]pyridine;5H-Cyclopenta[b]pyridine,6,7-dihydro-3-nitro-
• CAS NO: 84531-36-2
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.17
• Product Categories: Fused Ring Systems;Heterocycle-Pyridine series
• Mol File: 84531-36-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 94-95 °C
• Boiling Point: 277.921ºC at 760 mmHg
• Flash Point: 121.882ºC
• Appearance: /
• Density: 1.328g/cm3
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.15±0.20(Predicted)
• CAS DataBase Reference: 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE(84531-36-2)
• EPA Substance Registry System: 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE(84531-36-2)

Safety Data

• Hazardous Substances Data: 84531-36-2(Hazardous Substances Data)

Usage

General Description

3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE is a chemical compound that belongs to the class of nitro compounds. It is a highly reactive and potentially explosive compound that is commonly used in the production of pharmaceuticals and agrochemicals. The compound is characterized by its six-membered cyclic structure and the presence of a nitro group, which makes it an important building block for the synthesis of various organic compounds. Due to its potential hazards and reactivity, 3-NITRO-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE should be handled with caution and under strict safety protocols in laboratory and industrial settings.

InChI:InChI=1/C8H8N2O2/c11-10(12)7-4-6-2-1-3-8(6)9-5-7/h4-5H,1-3H2

Upstream product

• 14150-94-8 3,5-dinitro-1-methyl-2-pyridone 
• 120-92-3 cyclopentanone 
• 108-94-1 cyclohexanone 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 
• 7148-07-4 1-pyrrolidinocyclopent-1-ene 
• 126215-88-1 5-nitro-2-(pent-4-yn-1-yl)pyrimidine 
• 1614-92-2 1-(N-piperidino)cyclopentene 
• 14080-32-1 5-nitropyrimidine 

Downstream Products

• 1421429-82-4 phenyl 6,7-dihydro-5H-cyclopenta[b]pyridin-3-ylcarbamate 
• 178209-29-5 6,7-dihydro-5H-cyclopenta[b]pyridin-3-amine 

Relevant articles and documents

Synthesis, Characterization, and Rapid Cycloadditions of 5-Nitro-1,2,3-triazine

The synthesis, characterization, and a study of the cycloaddition reactions of 5-nitro-1,2,3-triazine (3) are reported. The electron-deficient nature of 3 permits rapid cycloaddition with a variety of electron-rich dienophiles, including amidines, enamines, enol ethers, ynamines, and ketene acetals in high to moderate yields. 1H NMR studies of a representative cycloaddition reaction between 3 and an amidine revealed a remarkable reaction rate and efficiency (1 mM, 3CN, 23 °C, >95%).

SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted bicyclic aromatic carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Nucleophilic reaction upon electron-deficient pyridone derivtives. X. One-pot synthesis of 3-nitropyridines by ring transformation of 1-methyl-3,5-dinitro-2-pyridone with ketones or aldehydes in the presence of ammonia

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